Evidence map›Paper›PMID 41505480›Full record

ArticlePloS one2026

Longitudinal analysis of the risk factors for onset and change in tinnitus in the Busselton Healthy Ageing Study.

Denise Fuchten, Inge Stegeman, Yinan Mao, Robert H Eikelboom, Michael L Hunter, Adriana L Smit

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Tinnitus in urban settings: insights into lifestyle and medical factors from the Hamburg City Health Study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Denise FuchtenDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-9326-6702
Inge StegemanDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands.
Yinan MaoDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands.
Robert H EikelboomEar Science Institute Australia, Subiaco, Australia.
Michael L HunterBusselton Health Study Centre, Busselton Population Medical Research Institute, Busselton, Australia.ORCID https://orcid.org/0000-0001-6704-4815
Adriana L SmitDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-9126-9969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEffective prevention and intervention strategies for tinnitus rely on identifying risk factors and understanding its progression over time. However, longitudinal data on these aspects are limited. This study therefore aimed to (1) assess the incidence of tinnitus and identify risk factors associated with tinnitus development, and (2) assess the impact of tinnitus and change in impact over time and identify factors associated with this change.

methodsData from the Busselton Healthy Ageing Study, a population-based cohort of individuals born between 1946-1964, were used. Information on tinnitus presence and impact, general health, ear-related health and mental health was collected from 3863 participants through questionnaires and physical measurements at two time points with a six-year interval. Logistic regression analysis was used to examine risk factors for tinnitus development. Multinomial logistic regression analysis was used to examine factors associated with changes in impact.

resultsThe 6-year incidence of tinnitus was 12.1%. Statistically significant risk factors for developing tinnitus included male gender, higher BMI, larger waist circumference, fair subjective health, hearing loss, occupational noise exposure with occasional use of hearing protection, hyperacusis, migraine, and diagnosed anxiety disorder. Among participants with pre-existing tinnitus, 21.4% reported an increase in tinnitus impact over time, while 16.5% experienced a decrease. Changes in impact were influenced by general health and ear-related health factors.

conclusionThe high incidence of tinnitus and its notable impact on daily life emphasize the importance of gaining a better understanding of the broad range of identified risk factors for developing tinnitus and change in impact. The multifaceted nature of these factors, comprising hearing-related issues, general health conditions and psychological aspects, underscore the complexity of tinnitus etiology and impact. By gaining more insight into these factors, we can inform future research efforts aimed at developing targeted prevention and intervention strategies tailored to specific demographic groups.

Indexed as

Healthy AgingTinnitusAgedFemaleHumansIncidenceLogistic ModelsLongitudinal StudiesMaleMiddle AgedRisk FactorsSurveys and Questionnaires

Identifiers

PMID41505480
PMCPMC12782377

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.