ArticlePloS one2026
PACT: A practice-driven predictive algorithm for customized transradial prosthetic socket design.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Toward predictive prosthetic socket modeling: Preliminary linear regression models of transradial limb-socket geometry.PLOS digital health · 2026Article
- Article
- Correction: PACT: A practice-driven predictive algorithm for customized transradial prosthetic socket design.PloS one · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Well-fitting sockets are crucial for successful upper-limb prosthesis use, yet current digital socket design workflows are not standardized and demand considerable clinician effort. In this study, we introduce the Predictive Algorithm for Customized Transradial Socket Design (PACT), which generates socket models from a 3D limb scan. It works by retrieving the most similar limb-socket pair from a reference library of prosthetist-designed prosthetic sockets and applying isotropic and anisotropic scaling adjustments to match the input limb. To validate the algorithm, the PACT-predicted sockets for 19 participants were compared to their prosthetist-designed ones (the clinical "gold standard") using the surface Euclidean (L2) distances, volume differences, and a 100-slice cross-sectional-area analysis. Localized discrepancies were mapped via signed-distance colorization and clustered with DBSCAN. PACT's outputs differed from prosthetist designs by 2.11 ± 0.51 mm on the surface and 2.74 ± 2.56% in volume on average; slice-wise area differences were within ±10% for most of the socket length, with larger errors near the proximal trimline and distal tip. Recurrent localized discrepancies were found to be concentrated at the anterior-distal trimline (15/19 cases) and anterior-posterior compression (11/19 cases), indicating clear targets for rule-based or measurement-informed refinements. Subgroup patterns suggested an age-related bias (undersizing in pediatric, oversizing in adults). Overall, PACT quickly delivers (13.2 ± 0.7 s) a first-draft transradial socket within commonly cited clinical fit tolerances. Focus on specific regions, along with metadata such as tissue stiffness, age, and clinician-led measurements, can improve personalization and generalizability in future iterations of the PACT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.