Evidence map›Paper›PMID 41505028›Full record

ReviewHead and neck pathology2026

Oral HPV-Related Epithelial Proliferation during Fingolimod Therapy: First Case Report and Review of the Literature.

Kittiphoj Tikkhanarak, Jay Saepoo, Nidhi Handoo, Emily Lanzel, Sherry Timmons, Ryan Frost, John Hellstein

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Head and neck pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kittiphoj TikkhanarakDepartment of Oral Pathology, Radiology and Medicine, College of Dentistry, The University of Iowa, Iowa City, IA, USA. kittiphoj-tikkhanarak@uiowa.edu.
Jay SaepooDepartment of Oral Pathology, Radiology and Medicine, College of Dentistry, The University of Iowa, Iowa City, IA, USA.
Nidhi HandooDepartment of Oral Pathology, Radiology and Medicine, College of Dentistry, The University of Iowa, Iowa City, IA, USA.
Emily LanzelDepartment of Oral Pathology, Radiology and Medicine, College of Dentistry, The University of Iowa, Iowa City, IA, USA.
Sherry TimmonsDepartment of Oral Pathology, Radiology and Medicine, College of Dentistry, The University of Iowa, Iowa City, IA, USA.
Ryan FrostGreenfield Dental, Greenfield, IA, USA.
John HellsteinDepartment of Oral Pathology, Radiology and Medicine, College of Dentistry, The University of Iowa, Iowa City, IA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fingolimod, an immunomodulatory agent used in the treatment of multiple sclerosis, has been associated with an increased risk of human papillomavirus (HPV)-related mucocutaneous lesions due to its immunosuppressive effects. We report the first documented case of oral mucosal HPV-related epithelial proliferation in a patient undergoing long-term fingolimod therapy. A 36-year-old male presented with multiple mildly papillomatous gingival lesions, during ongoing fingolimod (Gilenya

Indexed as

Fingolimod HydrochlorideImmunosuppressive AgentsMouth MucosaPapillomavirus InfectionsAdultHuman Papillomavirus VirusesHumansMaleMultiple SclerosisFingolimod HydrochlorideImmunosuppressive AgentsFingolimodGilenyaHPVHuman papilloma virusMultiple sclerosisOral

Identifiers

PMID41505028
PMCPMC12783387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.