Evidence map›Paper›PMID 41505015›Full record

ArticleTropical animal health and production2026

Mycobacterium bovis in the Dominican Republic, a study of detection, distribution and genomic variability.

Raysa Elena Reyes Santiago, María Jimena Marfil, Juan de la Cruz Araujo Lara, Yorkiris Consuegra Martínez, René Espinal Lagares, Luis Matos Casado, María Esther D'oleo, Martín José Zumárraga, Soledad Barandiaran

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tropical animal health and production, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Raysa Elena Reyes SantiagoInstituto de Enfermedades Infecciosas y Zoonóticas (IEIZ), Facultad de Ciencias Agronómicas y Veterinarias (FCAV), Universidad Autónoma de Santo Domingo (UASD), Santo Domingo, República Dominicana.
María Jimena MarfilFacultad de Ciencias Veterinarias, Cátedra de Enfermedades Infecciosas, Universidad de Buenos Aires, Av. Chorroarín 280, Buenos Aires, Agronomía CP:1427, Argentina. jmarfil@fvet.uba.ar.ORCID http://orcid.org/0000-0001-8134-7978
Juan de la Cruz Araujo LaraInstituto de Enfermedades Infecciosas y Zoonóticas (IEIZ), Facultad de Ciencias Agronómicas y Veterinarias (FCAV), Universidad Autónoma de Santo Domingo (UASD), Santo Domingo, República Dominicana.
Yorkiris Consuegra MartínezInstituto de Enfermedades Infecciosas y Zoonóticas (IEIZ), Facultad de Ciencias Agronómicas y Veterinarias (FCAV), Universidad Autónoma de Santo Domingo (UASD), Santo Domingo, República Dominicana.
René Espinal LagaresInstituto de Enfermedades Infecciosas y Zoonóticas (IEIZ), Facultad de Ciencias Agronómicas y Veterinarias (FCAV), Universidad Autónoma de Santo Domingo (UASD), Santo Domingo, República Dominicana.
Luis Matos CasadoFacultad de Ciencias Agronómicas y Veterinarias (FCAV), Instituto Nacional de Investigaciones Agropecuarias (INIA), Universidad Autónoma de Santo Domingo (UASD), Santo Domingo, República Dominicana.
María Esther D'oleoLaboratorio Veterinario Central (LAVECEN) División de Microbiología, Sección de Tuberculosis, Dirección General de Ganadería (DIGEGA), Ministerio de Agricultura, Santo Domingo, República Dominicana.
Martín José ZumárragaInstituto Nacional de Tecnología Agropecuaria, Instituto de Agrobiotecnología y Biología Molecular (IB-IABiMo), UEDD INTA-CONICET, Hurlingham, Buenos Aires, Argentina.
Soledad BarandiaranFacultad de Ciencias Veterinarias, Cátedra de Enfermedades Infecciosas, Universidad de Buenos Aires, Av. Chorroarín 280, Buenos Aires, Agronomía CP:1427, Argentina.

Funding

Fondo Nacional de Innovación y Desarrollo Científico-Tecnológico 2018-2019-2D2-178, 2020-2022
6 · The paper itself

Abstract

Bovine tuberculosis (bTB) real prevalence in the Dominican Republic is unknown. Cattle are infected with Mycobacterium bovis and this has been confirmed by bacteriological culture, but very scarce information is available regarding M. bovis genotypes. Here, 56 M. bovis isolates obtained from tissue samples collected in different regions of the country were analyzed. Additionally, direct PCR was assayed on samples from tissue with tuberculosis like lesion and from milk. Molecular confirmation and genotyping were used to identify M. bovis in isolates, tissue and milk samples. Seven different spoligotypes were detected, and the major variety of isolates was found in the northern region of the country, where dairy production is frequent. The most prevalent spoligotype was SB0140. These results supports the presence and dissemination of bTB in important cattle production regions in the Dominican Republic. Insights regarding cattle production and mandatory bTB testing are discussed and considerations that might enhance bTB control in the Dominican Republic are presented.

Indexed as

Genetic VariationMycobacterium bovisTuberculosis, BovineAnimalsCattleDominican RepublicGenotypeMilkPolymerase Chain ReactionPrevalenceBovine tuberculosisCaribbeanDiagnosisEpidemiological surveillanceSpoligotyping

Identifiers

PMID41505015
PMCPMC12783286

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.