Evidence map›Paper›PMID 41504785›Full record

Trial reportWorld journal of urology2026

Prospective single-center study comparing RealPulse

Charlotte Allaeys, Jasper Cornette, Edward Lambert, Geert De Naeyer, Peter Schatteman

Abstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Charlotte Allaeys *Urology, AZORG, Aalst, Belgium. charlotte.allaeys@ugent.be.ORCID http://orcid.org/0000-0002-4978-1405
Jasper Cornette *Urology, VITAZ, Sint-Niklaas, Belgium.ORCID http://orcid.org/0000-0001-7351-1096
Edward LambertUrology, AZORG, Aalst, Belgium.ORCID http://orcid.org/0000-0002-8627-4808
Geert De NaeyerUrology, AZORG, Aalst, Belgium.ORCID http://orcid.org/0000-0003-4118-8807
Peter SchattemanUrology, AZORG, Aalst, Belgium.ORCID http://orcid.org/0000-0001-5709-5643

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHolmium:YAG laser enucleation is the current golden standard for endoscopic enuclation of the prostate. Newer laser technologies, such as the RealPulse® Thulium:YAG system, offer different laser–tissue interactions that might affect enucleation efficiency and perioperative outcomes, yet comparative evidence remains limited. The aim of this study is to evaluate the clinical efficacy, safety profile, and short- and intermediate-term outcomes of both lasers.

methodsIn total, 98 men with benign prostatic obstruction, refractory to medication, were included between 13/12/2023 until 13/06/2024. Demographics, intra-operative, post-operative data and PROMs were prospectively collected. Patients were randomly assigned to Ho:YAG laser (group A) or to RealPulse® Tm:YAG laser (group B). SPSS version 29 (SPSS Inc. Chicago. IL, USA) was used to analyse all the data.

resultsNo significant difference in demographic and pre-operative parameters was found, except for prostate volume which was significantly higher in group B (p = 0.014). Similar enucleation efficiency, coagulation duration, enucleated tissue weight, catheterization time and hospital stay were seen with both lasers. The improvement of Qmax at 3 months postoperatively was similar in both groups (14.41 ± 9.38 in group A vs. 11.12 ± 10.74 in group B; p = 0.349). As well as the improvement in IPSS score at 6 weeks, 3 months and 1 year postoperatively. ICIQ-UI reports have a similar decline after 6 weeks with normalization on 3 months and 1 year.

conclusionThe Ho:YAG Laser and the RealPulse® Tm:YAG laser showed similar efficacy, safety and short- and intermediate-term outcomes.

Indexed as

Lasers, Solid-StateProstatectomyProstatic HyperplasiaAgedHumansLaser TherapyMaleMiddle AgedProspective StudiesThuliumTreatment OutcomeThuliumBenign prostatitic obstructionEnucleationHolmiumLaserProstateThulium

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.