Evidence map›Paper›PMID 41504745›Full record

ArticleMedical care2026

PCORnet®: 10 Years of Research Innovation.

Lauren W Cohen, Rowena J Dolor, Mark Weiner, Nadine Zemon, Charles Bailey, Thomas Carton, Erika Cottrell, Christopher B Forrest, Adrian F Hernandez, Rainu Kaushal and 6 more

Abstract read
In one paragraph

Article in Medical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lauren W CohenDuke Clinical Research Institute, Durham, NC.
Rowena J DolorDuke University School of Medicine, Durham, NC.
Mark WeinerWeill Cornell Medical College, New York, NY.
Nadine ZemonNadine Zemon, Patient Representative, Gainesville, FL.
Charles BaileyChildren's Hospital of Philadelphia, Philadelphia, PA.
Thomas CartonLouisiana Public Health Institute, New Orleans, LA.
Erika CottrellOregon Health and Science University, Portland, OR.
Christopher B ForrestChildren's Hospital of Philadelphia, Philadelphia, PA.
Adrian F HernandezDuke Clinical Research Institute, Durham, NC.
Rainu KaushalWeill Cornell Medical College, New York, NY.
Keith MarsoloDuke Clinical Research Institute, Durham, NC.
Kathleen McTigueUniversity of Pittsburgh Medical Center, Pittsburgh, PA.
Russell L RothmanVanderbilt University Medical Center, Nashville, TN.
Elizabeth ShenkmanUniversity of Florida at Gainesville, Gainesville, FL.
Lemuel R WaitmanSchool of Medicine, University of Missouri, Kansas City, MO.
on behalf of the PCORnet Steering Committee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe PCORnet® infrastructure was funded by PCORI in 2014 to streamline clinical trials, increase patient-centered research, and generate knowledge that leads to improved health care and outcomes. In this paper, we summarize the significant achievements of the infrastructure over the last decade as well as recent accomplishments. We also provide an update on the expanded patient population who receive care at sites participating in PCORnet® Clinical Research Networks (CRNs) and share priorities for the future.

methodsThe electronic health records of 71 health systems participating in PCORnet® CRNs as of July 2024 were queried, and data were analyzed to describe 10 common health conditions, stratified by demographic characteristics of age, sex, race, ethnicity, and an index of social deprivation.

resultsOut of over 100M total patients with activity in the last 10 years, health systems participating in PCORnet® CRNs had over 47 million unique patients with at least one encounter in 2023. The most common chronic conditions among these patients were hypertension (18%), anxiety disorders (10%), type 2 diabetes (8%), and asthma (5%). Over 20% of patients receiving care at a site participating in PCORnet were in the top 50% of metrics for area deprivation. The PCORnet infrastructure supported 51 PCORnet® studies, all of which met established guidelines for use of the PCORnet® Common Data Model (CDM), patient-engagement, and commitment to return of results. DISCUSSION: PCORnet® CRNs represent a diverse and expanding patient population and often include data on the socioeconomic status of the communities. Through continued efforts to engage communities and patients and national-scale research, the PCORnet® infrastructure can help improve care and outcomes for patients affected by common and rare conditions.

Indexed as

Biomedical ResearchPatient-Centered CareAdultAgedChronic DiseaseElectronic Health RecordsFemaleHumansMaleMiddle AgedUnited Statesnetworkspatient-centricityreal-world data

Identifiers

PMID41504745
PMCPMC12783338

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.