Evidence map›Paper›PMID 41504601›Full record

ArticleeLife2026

Cross-species evaluation of TANGO2 homologs, including HRG-9 and HRG-10 in

Sarah E Sandkuhler, Kayla S Youngs, Olivia Gottipalli, Laura D Owlett, Monica B Bandora, Aaliya Naaz, Euri Kim, Lili Wang, Andrew Wojtovich, Vandana Gupta and 2 more

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Sarah E SandkuhlerDepartment of Pathology, University of Rochester Medical Center, Rochester, United States.ORCID https://orcid.org/0000-0001-6799-9566
Kayla S YoungsDepartment of Neurology, University of Rochester Medical Center, Rochester, United States.
Olivia GottipalliEmory University, Atlanta, United States.
Laura D OwlettDepartment of Neurology, University of Rochester Medical Center, Rochester, United States.
Monica B BandoraMorgan State University, Baltimore, United States.
Aaliya NaazDepartment of Biology, Concordia University, Montreal, Canada.
Euri KimDepartment of Medicine, Brigham and Women's Hospital Harvard Medical School, Boston, United States.
Lili WangDepartment of Pharmacology, Vanderbilt University, Nashville, United States.ORCID https://orcid.org/0000-0002-2746-4521
Andrew WojtovichDepartment of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, Rochester, United States.
Vandana GuptaDepartment of Medicine, Brigham and Women's Hospital Harvard Medical School, Boston, United States.ORCID https://orcid.org/0000-0002-4057-8451
Michael SacherDepartment of Biology, Concordia University, Montreal, Canada.ORCID https://orcid.org/0000-0003-2926-5064
Samuel J MackenzieDepartment of Neurology, University of Rochester Medical Center, Rochester, United States.ORCID https://orcid.org/0000-0002-5571-7370

Funding

Child Neurologist Career Development Program (CNCDP)K12NS098482 · NINDS · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI SCHLAGGAR, BRADLEY L · 2016 to 2025
$26.2M
NIH HHS T32 GM007256NINDS NIH HHS 2K12NS098482-06NINDS NIH HHS K12 NS098482
6 · The paper itself

Abstract

Mutations in the

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsHemeAnimalsBiological TransportHumansOxidative StressSaccharomyces cerevisiaeZebrafishCaenorhabditis elegans ProteinsHemeC. eleganscell biologygeneticsgenomicsheme metabolismmetabolic dysfunctionmitochondriaoxidative stressrare diseaseS. cerevisiaeTANGO2 deficiencyzebrafish

Identifiers

PMID41504601
PMCPMC12782551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.