Evidence map›Paper›PMID 41504562›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2026

Current and Emerging Approaches and Technologies for Rapid Detection of Neisseria gonorrhoeae Antimicrobial Resistance.

Johan H Melendez, Yukari C Manabe

Abstract readReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Johan H MelendezDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland  USA.ORCID 0000-0001-6586-051X
Yukari C ManabeDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland  USA.ORCID 0000-0001-8619-5598

Funding

LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
TrainingU54EB007958 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI William Owen Osburn · 2007 to 2026
$34.6M
Characterizing Antimicrobial Resistance in Pharyngeal Neisseria gonorrhoeae Infections and the Role of Commensal Neisseria SpeciesK01AI153546 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MELENDEZ, JOHAN HUMBERTO · 2020 to 2024
$651k
NIAID NIH HHS UM1 AI068613NIBIB NIH HHS U54 EB007958NIH HHS K01AI153546NIH HHS U54EB007958
6 · The paper itself

Abstract

The increasing rates of antimicrobial resistance (AMR) in Neisseria gonorrhoeae (NG) pose a challenge to the successful future treatment of gonorrhea. Although antimicrobial susceptibility testing (AST) is not routinely performed for NG, detection of antimicrobial susceptibility at the point-of-care (POC) could help guide treatment, including the re-use of previously-recommended treatment. We review the landscape of commercially-available tests and those under development for the rapid determination of AMR in NG. Additionally, we discuss the performance of new and novel nucleic acid-based phenotypic approaches for rapid characterization of AMR, which could potentially be implemented at the POC for resistance-guided therapy. Lastly, issues regarding the implementation of POC tests for resistance testing are discussed.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialGonorrheaNeisseria gonorrhoeaeHumansMicrobial Sensitivity TestsMolecular Diagnostic TechniquesPoint-of-Care SystemsRapid Diagnostic TestsAnti-Bacterial Agents

Identifiers

PMID41504562
PMCPMC12781192

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.