Evidence map›Paper›PMID 41504481›Full record

ArticleMicrobiology spectrum2026

Clinical effect of in-house rapid diagnostic process on patients with bloodstream infections due to carbapenem-resistant bacteria or methicillin-resistant

Hongwei Pan, Xiaoyu Zhang, Yiwen Gao, Wei Li, Zhaogang Dong, Zhengdong Luo, Yong Li, Xiaoli Zhang, Yue Wu, Hongxia Zhou and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Hongwei Pan *Department of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.ORCID 0000-0002-0887-2239
Xiaoyu Zhang *Department of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Yiwen GaoDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Wei LiDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Zhaogang DongDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Zhengdong LuoDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Yong LiDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Xiaoli ZhangDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Yue WuDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Hongxia ZhouDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Ying WangDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Yue SunDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Yanyan LiuDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Miaomiao MiDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Enhua SunDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Hao WangDepartment of Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, China.ORCID 0000-0003-4493-3147
Yi ZhangDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.ORCID 0000-0002-0440-1798

Funding

Natural Science Foundation of China 82172339Natural Science Foundationof Shandong Province, China ZR2023MH123Taishan Scholar Program of Shandong Province of China tstp20221156
6 · The paper itself

Abstract

Bloodstream infections caused by multidrug-resistant bacteria result in a high mortality rate. Little research has been carried out to analyze the clinical effects of laboratory-based rapid identification and susceptibility tests of the types of organisms responsible for these infections. We previously developed an ammonium chloride-based in-house workflow for direct pathogen identification and susceptibility testing from positive blood cultures, eliminating the need for subsequent overnight subculturing. In this study, we carried out a prospective single-center cohort study evaluating the outcomes associated with in-house rapid detection of carbapenem-resistant bacterial strains or methicillin-resistant IMPORTANCE: In this study, we included only patients whose bloodstream infection was caused by carbapenem-resistant bacterial strains or methicillin-resistant

Indexed as

BacteremiaMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAdultAgedAged, 80 and overAnti-Bacterial AgentsBlood CultureCarbapenemsFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedProspective StudiesRapid Diagnostic TestsAnti-Bacterial AgentsCarbapenemsbloodstream infectionsclinical effectCROMRSArapid diagnostic

Identifiers

PMID41504481
PMCPMC12889151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.