ArticleFuture oncology (London, England)2026
Real-world management of oral mucositis/stomatitis among patients with advanced non-small cell lung cancer (NSCLC) or breast cancer (BC).
Article in Future oncology (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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11 authors.
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Abstract
aimsTo describe United States real-world oral mucositis/stomatitis (OM/S) management for patients with non-small cell lung cancer (NSCLC) or breast cancer (BC) and document physician awareness of OM/S guidelines, risk factors, and barriers to care. PATIENTS &
methodsThis study included a cross-sectional physician survey and retrospective chart review. Physicians completed an electronic survey and abstracted chart data for patients with advanced/metastatic NSCLC or BC who developed treatment-related OM/S on or after 1 January 2021.
resultsThirty-one physicians abstracted data for 272 patients (146 NSCLC; 126 BC). Median patient age at OM/S event was 66.2 years (NSCLC) and 61.6 years (BC). Systemic treatments included chemotherapy (NSCLC: 86.3%; BC: 67.5%), immunotherapy (NSCLC: 56.8%; BC: 10.3%), and targeted therapy (NSCLC: 9.6%; BC: 46.8%). OM/S-related treatment changes (reduction/interruption/discontinuation) were reported in 20.5% and 35.7% of patients with NSCLC or BC, respectively. A majority of physicians (61.3%) were unaware of published OM/S management guidelines. Physicians identified poor oral hygiene (80.6%) and limited physician awareness of OM/S guidelines (71.0%) as barriers to OM/S management.
conclusionsOM/S occurs across cancer treatment regimens and can lead to treatment modification. Improvements in OM/S management at the patient and provider level are needed to enhance care and improve clinical outcomes.
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