Evidence map›Paper›PMID 41504259›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

CD20

Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Benjian ZhangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Xiaotian YuanDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Kelei GaoDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Bo YouInstitute of Otolaryngology Head and Neck Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, P. R. China.
Yaxuan WangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Lai MengDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Zirong ChenDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Shaobing XieDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Yunqing LiuDepartment of Oncology, Xiangya Third Hospital of Central South University, Changsha, P. R. China.
Zijian DongSchool of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, P. R. China.
Shumin XieDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Ruohao FanDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Fengjun WangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Junyi ZhangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Zhihai XieDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Yongzhen MoDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Hua ZhangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.
Weihong JiangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, P. R. China.ORCID https://orcid.org/0000-0002-3854-8923

Funding

Central South University Graduate Students Independent Exploration and Innovation Project 1053320222011National Natural Science Foundation of China 82171118National Natural Science Foundation of China 82403801Natural Science Foundation of Hunan Province 2021JJ41027Natural Science Foundation of Hunan Province 2024JJ6631
6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is a malignant tumor characterized by extensive immune cell infiltration. However, the function and significance of B cells in NPC have been overlooked. Exploring B cells and their interactions with other immune cells will provide deeper insights into the immune microenvironment of NPC and theories of immunotherapy.We utilized single-cell sequencing data to identify characteristic B cell subtypes of NPC. Subsequently, the presence of the CD20

Indexed as

B-LymphocytesCD8-Positive T-LymphocytesHistocompatibility Antigens Class INasopharyngeal CarcinomaNasopharyngeal NeoplasmsAnimalsAntigens, CD20Cell Line, TumorHumansImmunotherapyInterferon-gammaMiceMice, Inbred BALB CReceptors, FcTumor MicroenvironmentAntigens, CD20FCRL4 protein, humanHistocompatibility Antigens Class IInterferon-gammaReceptors, Fcantigen presentationB cellsCD8+ T cellsimmunotherapynasopharyngeal carcinoma

Identifiers

PMID41504259
PMCPMC12955863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.