Evidence map›Paper›PMID 41504140›Full record

ArticleChemistry & biodiversity2026

Analysis of the Chemical Composition and Glycolipid Metabolism-Regulating Properties of Centella asiatica.

Xin Jin, Jie Zang, Ang Li, Yuanyuan Yao, Zhaoyuan Dai, Xinchi Feng, Feng Qiu

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xin JinSchool of Chinese Materia Medica, Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Jie ZangSchool of Chinese Materia Medica, Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Ang LiSchool of Chinese Materia Medica, Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Yuanyuan YaoSchool of Chinese Materia Medica, Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Zhaoyuan DaiSchool of Chinese Materia Medica, Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Xinchi FengSchool of Chinese Materia Medica, Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.ORCID https://orcid.org/0000-0002-3522-0471
Feng QiuSchool of Chinese Materia Medica, Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Funding

National Natural Science Foundation of China 82374140Science & Technology Development Fund of Tianjin Education Commission for Higher Education 2022KJ157
6 · The paper itself

Abstract

As a traditional Chinese medicine, Centella asiatica (CA) contains diverse chemical constituents, which serve as the basis for its broad-spectrum pharmacological activities. This study aimed to investigate the therapeutic effects of CA on glycolipid metabolism disorders in ob/ob mice and conduct a systematic qualitative and quantitative analysis of the chemical composition of CA. The results demonstrated that CA extract effectively ameliorated glucose intolerance and insulin resistance, decreased blood lipid levels, and alleviated hepatic steatosis in ob/ob mice. A total of 39 chemical constituents were identified in the CA extract. To facilitate the quality evaluation of CA, we established a rapid and precise method for the simultaneous quantification of eight target compounds-asiaticoside, asiaticoside B, madecassoside, asiatic acid, madecassic acid, stachyose, kaempferol glucuronide, and quercetin-3-O-glucuronide in CA medicinal materials. Notably, this study represents the first quantitative analysis of stachyose, kaempferol glucuronide, and quercetin-3-O-glucuronide in CA, thereby complementing and expanding the existing framework for its quality control.

Indexed as

CentellaGlycolipidsTriterpenesAnimalsChromatography, High Pressure LiquidMiceGlycolipidsTriterpenesCentella asiaticaglycolipid metabolism regulatingquantitative analysis methodUPLC‐MS/MS

Identifiers

PMID41504140
PMCPMC13419880

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.