Evidence map›Paper›PMID 41503954›Full record

ReviewChemistry & biodiversity2026

Essential Oils as an Alternative to Synthetic Antiseptics in Cosmetics and Personal Care Products.

Ugiloy Yusupova, Durdona Tojiboeva, Rimma Mukhamatkhanova, Dilnoza Dusmatova

Abstract readReview
In one paragraph

Review in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ugiloy YusupovaInstitute of the Chemistry of Plant Substances, Tashkent, Uzbekistan.ORCID https://orcid.org/0000-0003-3401-2379
Durdona TojiboevaInstitute of the Chemistry of Plant Substances, Tashkent, Uzbekistan.
Rimma MukhamatkhanovaInstitute of the Chemistry of Plant Substances, Tashkent, Uzbekistan.
Dilnoza DusmatovaInstitute of the Chemistry of Plant Substances, Tashkent, Uzbekistan.

Funding

Ministry of Higher Education, Science and Innovations of the Republic of Uzbekistan AL-8624042469
6 · The paper itself

Abstract

Essential oils (EOs) are volatile aromatic compounds highly valued in cosmetics due to their multifunctional biological activity and long history of use. Because of their rich chemical composition and wide spectrum of action, EOs protect the skin, support regeneration, and serve as natural preservatives. Historically, plants rich in EOs were used to refresh and soothe the skin, and Cleopatra is often mentioned as an early example of their use. Today, EOs are extensively incorporated into cosmetics due to their antimicrobial, antioxidant, and regenerative properties. Their complex composition enables them to function both as natural preservatives and as active agents that promote skin health. Growing concerns over the safety of synthetic preservatives have driven consumers toward plant-based alternatives, increasing interest in EO-based formulations. Modern techniques such as nanoencapsulation and polymeric carrier systems are now used to enhance the stability, bioavailability, and safety of these oils, reducing potential skin irritation. However, challenges remain due to compositional variability, limited toxicological data, and regulatory complexity. Despite these issues, EOs continue to be regarded as promising eco-friendly ingredients for next-generation cosmetics. This review covers their chemical diversity, biological properties and potential as natural antiseptics compared with conventional synthetic agents, underlining recent advances made in their cosmetic applications.

Indexed as

Anti-Infective Agents, LocalCosmeticsOils, VolatileHumansPersonal Care ProductsAnti-Infective Agents, LocalCosmeticsOils, VolatilePersonal Care Productsclean beautyessential oilsformulation/stabilitymicrobiologynatural preservativessafety testing

Identifiers

PMID41503954
PMCPMC13420247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.