Evidence map›Paper›PMID 41503622›Full record

ArticleData in brief2026

Datasets of 16S rRNA gene amplicon sequences, metabolites, and soluble immune components in bronchoalveolar lavage samples from severe asthmatic and age-matched control children.

Mélanie Briard, Blanche Guillon, Eric Venot, Marta Grauso, Aurélia Bruneau, Marie-Noëlle Rossignol, François Fenaille, Florence Castelli, Muriel Thomas, Guillaume Lezmi and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mélanie BriardUniversité Paris-Saclay, CEA, INRAE, UMR Département Médicaments et Technologies pour la Santé (DMTS)/SPI/Laboratoire d'Immuno-Allergie Alimentaire, 91191 Gif-sur-Yvette, France.
Blanche GuillonUniversité Paris-Saclay, CEA, INRAE, UMR Département Médicaments et Technologies pour la Santé (DMTS)/SPI/Laboratoire d'Immuno-Allergie Alimentaire, 91191 Gif-sur-Yvette, France.
Eric VenotUniversité Paris-Saclay, CEA, INRAE, UMR Département Médicaments et Technologies pour la Santé (DMTS)/SPI/Laboratoire d'Immuno-Allergie Alimentaire, 91191 Gif-sur-Yvette, France.
Marta GrausoUniversité Paris-Saclay, CEA, INRAE, UMR Département Médicaments et Technologies pour la Santé (DMTS)/SPI/Laboratoire d'Immuno-Allergie Alimentaire, 91191 Gif-sur-Yvette, France.
Aurélia BruneauINRAE, Université Paris-Saclay, AgroParisTech, UMR1319 Micalis Institute, 78350 Jouy-en-Josas, France.
Marie-Noëlle RossignolUniversité Paris Saclay, INRAE, AgroParisTech, UMR1313 GABI, 78350 Jouy en Josas, France.
François FenailleUniversité Paris-Saclay, CEA, INRAE, UMR Département Médicaments et Technologies pour la Santé (DMTS)/SPI/Laboratoire innovations en spectrométrie de masse pour la santé, MetaboHUB, 91191 Gif-sur-Yvette, France.
Florence CastelliUniversité Paris-Saclay, CEA, INRAE, UMR Département Médicaments et Technologies pour la Santé (DMTS)/SPI/Laboratoire innovations en spectrométrie de masse pour la santé, MetaboHUB, 91191 Gif-sur-Yvette, France.
Muriel ThomasINRAE, Université Paris-Saclay, AgroParisTech, UMR1319 Micalis Institute, 78350 Jouy-en-Josas, France.
Guillaume LezmiAP-HP, Hôpital Necker-Enfants Malades, Service de Pneumologie et Allergologie Pédiatriques, Paris, France.
Maria Leite-de-MoraesUniversité de Paris Cité, Institut Necker Enfants Malades, Equipe Immunorégulation et Immunopathologie, Inserm UMR1151, CNRS UMR8253, F-75015, Paris, France.
Karine Adel-PatientUniversité Paris-Saclay, CEA, INRAE, UMR Département Médicaments et Technologies pour la Santé (DMTS)/SPI/Laboratoire d'Immuno-Allergie Alimentaire, 91191 Gif-sur-Yvette, France.
Vinciane Saint-CriqINRAE, Université Paris-Saclay, AgroParisTech, UMR1319 Micalis Institute, 78350 Jouy-en-Josas, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe asthma (SA) is a heterogeneous condition characterized by multiple phenotypes, each characterized by different endotypes. Understanding the mechanisms occurring in the lungs of children with SA can help in understanding pathogenesis and in providing the most effective therapeutic strategies. This article describes microbiota, metabolites, and soluble immune components assessed in bronchoalveolar lavage (BAL) fluids from children with severe asthma (

Indexed as

Bronchoalveolar lavageChildrenCytokinesMetabolomicsMicrobiome

Identifiers

PMID41503622
PMCPMC12769396

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.