Evidence map›Paper›PMID 41503533›Full record

ArticleASM case reports2026

Management of an infection from NDM-1-producing

Alison M Hixon, Sumanth Gandra, Rebekah E Dumm

Abstract readCase Reports
In one paragraph

Article in ASM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alison M HixonDivision of Infectious Disease, Washington University, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0002-8373-4311
Sumanth GandraDivision of Infectious Disease, Washington University, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0003-1482-0854
Rebekah E DummPathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0003-3139-3153

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infections with New Delhi metallo-beta-lactamase (NDM)-producing Enterobacterales are increasingly reported in the United States, with some isolates being reported susceptible to aztreonam (ATM) alone. However, data for the use of ATM as monotherapy are lacking, and current guidelines recommend the use of cefiderocol (FDC) or ceftazidime-avibactam (CZA) plus ATM for severe infections due to concern for co-production of serine beta-lactamases. Case Summary: Here, we report a case of necrotizing soft tissue and surgical hardware infection in an immunocompromised patient with NDM-1-producing Conclusion: This case demonstrates the potential efficacy of ATM therapy, at least for part of the treatment course. Further studies are needed regarding treatment outcomes for ATM-susceptible NDM-producing Enterobacterales infections.

Indexed as

antibiotic resistanceaztreonamNDM

Identifiers

PMID41503533
PMCPMC12772298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.