Evidence map›Paper›PMID 41503524›Full record

ArticleASM case reports2026

Successful desensitization to liposomal amphotericin B for the treatment of disseminated cryptococcosis in pregnancy: a case report.

Susanne O Ajao, Julia M Nelson, Arsheena Yassin, Emily B Rosenfeld, Justin S Brandt, Catherine Monteleone, Pinki J Bhatt, Ahmed Abdul Azim

Abstract readCase Reports
In one paragraph

Article in ASM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Susanne O Ajao *Division of Allergy, Immunology, and Infectious Diseases, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.ORCID https://orcid.org/0009-0004-8990-1434
Julia M Nelson *Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.ORCID https://orcid.org/0009-0009-6182-0786
Arsheena YassinRobert Wood Johnson University Hospital, New Brunswick, New Jersey, USA.ORCID https://orcid.org/0000-0002-5039-6301
Emily B RosenfeldDivision of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Justin S BrandtDepartment of Obstetrics and Gynecology, NYU Grossman School of Medicine, New York, New York, USA.
Catherine MonteleoneDivision of Allergy, Immunology, and Infectious Diseases, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Pinki J BhattDivision of Allergy, Immunology, and Infectious Diseases, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Ahmed Abdul AzimDivision of Allergy, Immunology, and Infectious Diseases, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.ORCID https://orcid.org/0000-0001-7940-4320

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cryptococcosis is the most common opportunistic fungal infection in people with human immunodeficiency virus. On a global scale, it causes 15% of acquired immunodeficiency syndrome-related mortality. Case Summary: We report the case of a 21-year-old cisgender pregnant woman living with human immunodeficiency virus who presented with headache and photophobia. Her clinical course was complicated by recurrent hospital admissions for disseminated cryptococcosis and a life-threatening reaction to liposomal amphotericin B, the mainstay of treatment. A desensitization protocol was implemented, allowing for continuation of therapy during pregnancy. Conclusion: The management of cryptococcosis in pregnancy is challenging due to the potential teratogenic effects of antifungals used and the limited therapeutic options available. This case highlights the complexities of treatment in pregnancy and demonstrates successful desensitization to liposomal amphotericin B during pregnancy.

Indexed as

AIDSallergyamphotericin B lipid complexcryptococcosisdesensitizationHIVliposomal amphotericin Bpregnancy

Identifiers

PMID41503524
PMCPMC12772304

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.