ArticleJournal of the Endocrine Society2026
Urinary Proteomics as a Noninvasive Readout of Obesity-associated Inflammation.
Article in Journal of the Endocrine Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Obesity affects a large percentage of the population, and it is associated with many comorbidities. These pathologies often coincide with the presence of a low-grade chronic inflammatory state in individuals with obesity that can be measured using circulating inflammatory proteins. The objective of this study was to use a noninvasive approach to determine obesity-induced inflammation by measuring the urinary proteome of individuals with and without obesity. Methods: Morning urine samples were taken from normal-weight controls (n = 30) with a mean body mass index (BMI) of 22.8 kg/m Results: Of the 384 inflammation proteins, 48 proteins had a Conclusion: This paper shows that urine may represent a novel noninvasive approach to measure the state of inflammation in individuals with obesity using Olink targeted proteomics.
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