ArticleRSC advances2026
Evaluating the biological characteristics of targeted ZIF-8-encapsulated individual and combined drug systems for enhanced
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Metal-Organic Frameworks in Food Biotechnology: Opportunities, Challenges, and Future Perspectives for Probiotic Delivery, Precision Fermentation, and Circular Food Systems.Nanomaterials (Basel, Switzerland) · 2026Review
Corrections and comments
- Expression of concern
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The management of toxicity, and the fulfillment of safety requirements are considered as the most prominent challenges associated with cancer drug delivery. This study introduces a novel pH-responsive nanoparticle system based on ZIF-8 for the co-delivery of a ruthenium(ii) polypyridyl complex (RuPIP) and olaparib (Olap), which is designed for enhanced therapeutic efficacy and reduced systematic toxicity. To improve their biocompatibility and targeting, the nanoparticles were surface-coated with folic acid ligand, yielding the final RuPIP-Olap@ZIF-8-FA formulation. The RuPIP-Olap@ZIF-8 nanoparticles were fabricated through a rapid, eco-friendly method, and they achieved high co-loading capacities of 20.59% ± 1.38% for RuPIP and 10.77% ± 1.00% for Olap, as confirmed by HPLC analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.