In one paragraphArticle in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
42 authors.
Thomas R GoddardDepartment of Respiratory and Sleep Medicine, Women's and Children's Hospital, 72 King William Rd, Adelaide, SA, 5042, Australia.ORCID 0000-0002-7062-843X Jessica Ap Carlson-JonesFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0002-2862-0338 Morton JudithDepartment of Thoracic Medicine, The Royal Adelaide Hospital, 1 Port Road, Adelaide, SA, 5000, Australia.ORCID 0000-0002-1715-5573 Chee Y OoiDiscipline of Paediatrics and Child Health, School of Clinical Medicine, UNSW Medicine and Health, University of New South Wales, 55 Botany Street, Randwick, NSW, 2031, Australia.ORCID 0000-0001-7111-0926 Tai AndrewDepartment of Respiratory and Sleep Medicine, Women's and Children's Hospital, 72 King William Rd, Adelaide, SA, 5006, Australia.ORCID 0000-0001-9240-5416 Morgyn S WarnerMicrobiology & Infectious Diseases, SA Pathology, 1 Port Road, Adelaide, SA, 5000, Australia.ORCID 0000-0002-4053-1610 Wong JohnDepartment of Respiratory and Sleep Medicine, Women's and Children's Hospital, 72 King William Rd, Adelaide, SA, 5006, Australia.
Ieuan Es EvansAdult Cystic Fibrosis Centre, The Prince Charles Hospital, 627 Rode Road, Brisbane, QLD, 4032, Australia.ORCID 0000-0002-9669-0805 Emily HopkinsDepartment of Thoracic Medicine, The Royal Adelaide Hospital, 1 Port Road, Adelaide, SA, 5000, Australia.ORCID 0000-0003-0736-4766 Jonathan R IredellPhage Australia, Westmead Institute for Medical Research, 176 Hawkesbury Rd, Sydney, NSW, 2145, Australia.ORCID 0000-0003-2469-7060 Hubertus Pa JersmannDepartment of Respiratory and Sleep Medicine, Women's and Children's Hospital, 72 King William Rd, Adelaide, SA, 5006, Australia.ORCID 0000-0003-1763-2736 Katrine L WhitesonCharle Dunlop School of Biological Sciences, University of California, Irvine, 3236 McGaugh Hall, Irvine, CA, 92697, USA.ORCID 0000-0002-5423-6014 George BourasThe Department of Surgery - Otolaryngology Head and Neck Surgery, University of Adelaide and the Basil Hetzel Institute for Translational Health Research, Central Adelaide Local Health Network, Adelaide, SA, 5000, Australia.ORCID 0000-0002-5885-4186 Michael P DoaneFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0001-9820-2193 Nicholas W FalkFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0003-2180-7359 Renee GreenFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0009-0001-8287-1955 Susanna R GrigsonFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0003-4738-3451 Vijini MallawaarachchiFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0002-2651-8719 Belinda MartinFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0003-4696-1694 Michael J RoachCollege of Medicine and Public Health, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0003-1488-5148 Feargal J RyanCollege of Medicine and Public Health, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0002-1565-4598 Anita TarasenkoFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0009-0003-4283-2374 Bhavya PapudeshiFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0001-5359-3100 Barbara DrigoSchool of Agriculture, Food and Wine, Adelaide University, 31 Hartley Grove, Urrbrae, SA, 5064, Australia.ORCID 0000-0002-3301-0470 Sarah K GilesFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0002-4395-060X Clarice M HarkerCollege of Medicine and Public Health, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0009-0008-6802-6799 Ryan D HesseFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0001-9366-5631 Riley J HodgsonCollege of Science and Engineering, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0002-8043-2473 Art HussnainSchool of Agriculture, Food and Wine, Adelaide University, Plant Genomics Centre, Hartley Grove, Urrbrae, SA, 5064, Australia.ORCID 0009-0000-6513-3638 Abbey HuttonFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0002-2474-1327 Laura K InglisFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0001-7919-8563 Christopher KeneallyEnvironment Institute, Adelaide University, North Terrace, Adelaide, SA, 5005, Australia.ORCID 0000-0001-7261-6259 Emma N KerrFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0002-1446-4282 Craig LiddicoatCollege of Science and Engineering, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0002-4812-7524 Shawn D PeddleCollege of Science and Engineering, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0003-3464-3058 Carl D WatsonCollege of Science and Engineering, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0002-7721-2162 Przemysław DecewiczLaboratory of Applied Microbial Ecology, Institute of Microbiology, Faculty of Biology, University of Warsaw, I. Miecznikowa 1, Warsaw, 02-096, Poland.ORCID 0000-0002-5621-7124 Peter G SpeckCollege of Science and Engineering, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0001-9087-258X James G MitchellFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0002-8445-0935 Elizabeth A DinsdaleFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0002-2177-203X Robert A EdwardsFlinders Accelerator for Microbiome Exploration, Flinders University, Sturt Road, Bedford Park, SA, 5042, Australia.ORCID 0000-0001-8383-8949 Funding
Computational and Experimental Resources for Virome Analysis in Inflammatory Bowel Disease (CERVAID)RC2DK116713 · NIDDK · WASHINGTON UNIVERSITY · PI WANG, DAVID · 2019 to 2023
$8.9MNIDDK NIH HHS RC2 DK116713
6 · The paper itselfAbstract
Chronic infections in cystic fibrosis (CF) emerge from gradual ecological transitions in the airway microbiome, yet early predictive markers remain poorly defined. We developed a new autoencoder-based framework that outperforms read-based or metagenome-assembled genome-based analyses at capturing the continuum from health-associated commensals to pathogen-dominated, antibiotic-tolerant communities. This improvement is achieved by integrating taxonomic and functional data from 127 sputum and bronchoalveolar lavage metagenomes from 64 people with CF into latent "Clusters of Phylogeny and Functions" (COPFs). Coupled with gradient-boosted random forests, COPFs predicted
Identifiers
PMID41503489
PMCPMC12772665
What OpenQuestion holds
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