ArticleJournal of neurological surgery. Part B, Skull base2026
The Use of Fibrin Sealants in Reducing Postoperative Complications in Skull Base Surgery: A Systematic Review and Meta-Analysis.
Article in Journal of neurological surgery. Part B, Skull base, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- TachoSilNeurosurgical review · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To determine if using fibrin sealants (FS) during skull base (SB) surgery reduces complications. Methods: PubMed, Cochrane, Web of Science, and Embase databases were searched for studies of patients who underwent SB surgery with use of an FS. A systematic review was conducted according to PRISMA guidelines. Primary outcomes included incidence of cerebrospinal fluid (CSF) leak, revision surgery, infection, and drain placement. Methods for meta-analysis were performed including tests of homogeneity and both fixed-effects and random-effects models. Results: A total of 30 articles met the inclusion criteria. There were 3,681 patients, including 2,220 patients who received FS and 1,461 patients who did not. The most common surgical approaches were posterior fossa (27.4%) and transsphenoidal (18.2%). The FS group was less likely to have a lumbar drain placed (1.7% versus 8.1% of the control group). The difference in drain placement incidence between groups for the studies which included both groups was -0.135 (95% CI [-0.285, 0.016], Conclusion: Patients who underwent SB surgery with FS may have lower incidences of drain placement than patients whose surgery did not involve FS.
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