Evidence map›Paper›PMID 41503417›Full record

ArticleJournal of neurological surgery. Part B, Skull base2026

Added Sinonasal Morbidity of Transpterygoid Approach versus Transsphenoidal Approach: A Case-Controlled Analysis.

Jasmeet Saroya, Alice E Huang, Farideh Hooseinzadeh, Christine K Lee, Juan Fernandez-Miranda, Peter H Hwang, Zara M Patel, Jayakar V Nayak, Michael T Chang

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurological surgery. Part B, Skull base, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jasmeet SaroyaDepartment of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States.ORCID 0009-0008-8064-774X
Alice E HuangDepartment of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States.
Farideh HooseinzadehDepartment of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States.
Christine K LeeDepartment of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States.
Juan Fernandez-MirandaDepartment of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States.
Peter H HwangDepartment of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States.
Zara M PatelDepartment of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States.ORCID 0000-0003-2072-982X
Jayakar V NayakDepartment of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States.
Michael T ChangDepartment of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States.ORCID 0000-0001-9519-5880

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The transpterygoid approach is often used alongside the transsphenoidal approach in endoscopic endonasal skull base surgery to access lateral skull base regions. This study investigates the sinonasal morbidity associated with this combined approach. Methods: We conducted a retrospective analysis of 70 adult patients who underwent either transsphenoidal (TS) or transsphenoidal plus transpterygoid (TS + TP) approaches at a tertiary academic hospital from 2018 to 2023. Sinonasal quality of life was measured using the Sinonasal Outcome Test (SNOT-22) at preoperative, 2-week, 6-week, and 12-week postoperative evaluations. Results: Both cohorts exhibited a significant increase in SNOT-22 scores at 2 weeks postoperatively (TS: mean increase of 8.5, Conclusion: The transpterygoid approach, when added to the transsphenoidal approach, does not increase long-term sinonasal morbidity. This suggests that the combined approach is a viable option for achieving broader surgical exposure without compromising sinonasal quality of life in the long term. Further studies with extended follow-up are needed to confirm these findings and explore additional quality of life metrics.

Indexed as

endoscopic endonasal skull base surgerymiddle turbinate sacrificeretrospective analysissinonasal morbiditysinonasal outcomessinonasal quality of lifeskull base surgerySNOT-22transpterygoid approachtranssphenoidal approach

Identifiers

PMID41503417
PMCPMC12774503

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.