Evidence map›Paper›PMID 41503372›Full record

ArticleInfectious Disease Modelling2026

Integrating Kolmogorov-Arnold networks with ordinary differential equations for efficient, interpretable, and robust deep learning: Epidemiology of infectious diseases as a case study.

Kexin Ma, Xu Lu, Nicola Luigi Bragazzi, Dominik Selzer, Thorsten Lehr, Biao Tang

Abstract read
In one paragraph

Article in Infectious Disease Modelling, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. KKANs: Ku̇rková-Kolmogorov-Arnold networks and their learning dynamics.Neural networks : the official journal of the International Neural Network Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kexin MaSchool of Mathematics and Statistics, Xi'an Jiaotong University, Xi'an, 710049, People's Republic of China.
Xu LuInstitute for Financial Studies and School of Mathematics, Shandong University, Jinan, 250100, People's Republic of China.
Nicola Luigi BragazziDepartment of Clinical Pharmacy, Saarland University, 66123, Saarbrücken, Germany.
Dominik SelzerDepartment of Clinical Pharmacy, Saarland University, 66123, Saarbrücken, Germany.
Thorsten LehrDepartment of Clinical Pharmacy, Saarland University, 66123, Saarbrücken, Germany.
Biao TangSchool of Mathematics and Statistics, Xi'an Jiaotong University, Xi'an, 710049, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study extends universal differential equation (UDE) frameworks by integrating the Kolmogorov-Arnold Network (KAN) with ordinary differential equations, referred to as KAN-UDE, to achieve efficient and interpretable deep learning. Our case study centers on the epidemiology of emerging infectious diseases. Compared to UDEs based on multi-layer perceptrons, training KAN-UDE models shows significantly improved fitting performance, as evidenced by a rapid and substantial reduction in loss. KAN-UDE models demonstrate accurate reconstruction of nonlinear functions under partial time-series training data, maintaining robustness to data sparsity. This approach enables an interpretable learning process, as KAN-UDE models were reconstructed as fully mechanistic models (RMMs). While KAN-UDE models exhibit lower robustness and accuracy when real-world data randomness is considered, RMMs predict epidemic trends robustly and accurately over much longer time windows, as KAN precisely reconstructs the mechanistic functions despite data randomness.

Indexed as

Deep learningEpidemiologyKANKAN-UDEMechanistic models

Identifiers

PMID41503372
PMCPMC12771098

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.