Evidence map›Paper›PMID 41503350›Full record

ArticleNorth American Spine Society journal2026

Impact of sarcopenia and multifidus atrophy on outcomes from minimally invasive decompression surgery for lumbar spinal stenosis.

Gilad J Regev, Uri Hochberg, Dror Ofir, Khalil Salame, Zvi Lidar, Morsi Khashan

Abstract read
In one paragraph

Article in North American Spine Society journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gilad J RegevDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
Uri HochbergDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
Dror OfirDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
Khalil SalameDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
Zvi LidarDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
Morsi KhashanDepartment of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In order to improve outcomes for patients with lumbar spinal stenosis, identification of better prognostic factors is necessary to guide patient selection for surgery. The purpose of this study was to investigate the prognostic value of multifidus atrophy and sarcopenia on postoperative pain and disability following minimally invasive decompression for lumbar spinal stenosis. Methods: We retrospectively reviewed medical records and imaging studies for patients with lumbar spinal stenosis who underwent minimally invasive tubular decompression. Multifidus total cross sectional area (tCSA), multifidus functional cross sectional area (fnCSA), multifidus fatty infiltration (FI), psoas tCSA, and psoas relative cross sectional area (rCSA) were evaluated by univariable and multivariable regression to identify predictors of postoperative improvement in visual analogue scores for back pain (VASB) and leg pain (VASL) and Oswestry disability index (ODI) scores for disability. Results: Minimally invasive decompression was performed at 75 spinal levels in 64 patients with an average age of 70.1±10.0 years. In multivariable analysis, lower multifidus FI was significantly associated with 5 point improvement in ODI (p=.002), 10 point improvement in ODI (p=.017), and 17 point improvement in ODI (p=.044). Only male gender (p=.030), lower preoperative VASB (p=.001), and lower preoperative VASL (p=.015) were independently predictive of postoperative deterioration in ODI, VASB, and VASL, respectively. Conclusions: Multifidus FI predicts postoperative improvement in disability following minimally invasive decompression for lumbar spinal stenosis with high accuracy. Minimally invasive decompression surgery is effective for elderly patients and sarcopenic patients, who are not at risk for poorer postoperative outcomes. Male gender and lower preoperative pain or disability are risk factors for postoperative deterioration in patient-reported outcomes.

Indexed as

Cross sectional areaFatty infiltrationLumbar spinal stenosisMinimally invasive spine surgeryMultifidus atrophySarcopenia

Identifiers

PMID41503350
PMCPMC12769823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.