Evidence map›Paper›PMID 41503305›Full record

ArticleCureus2025

A Novel Intensity-Modulated Radiation Therapy Approach to Reduce Tongue Radiation Dose Using the BinkieRT Intraoral Device: A Case Report.

Kanta Shiojima, Seiya Isozaki, Toshiaki Matsui, Takumi Kodama, Shigehiro Kudo

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kanta ShiojimaRadiation Oncology, Saitama Cancer Center, Saitama, JPN.
Seiya IsozakiRadiation Oncology, Saitama Cancer Center, Saitama, JPN.
Toshiaki MatsuiRadiation Oncology, Saitama Cancer Center, Saitama, JPN.
Takumi KodamaRadiation Oncology, Saitama Cancer Center, Saitama, JPN.
Shigehiro KudoRadiation Oncology, Saitama Cancer Center, Saitama, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation therapy plays a pivotal role in the management of oral cancer. However, radiation-induced mucositis and dysgeusia frequently impair patients' quality of life. To mitigate these risks, intraoral positioning devices have been introduced to minimize radiation exposure to the oral organs at risk. We report a case of recurrent buccal mucosa cancer treated with intensity-modulated radiation therapy (IMRT) using a commercial intraoral device, BinkieRT (Paprica Lab., Seoul, Republic of Korea). The device displaced the tongue contralaterally and separated the oral cavity from the target volume, leading to a reduction in radiation dose to the tongue and oral mucosa without compromising target coverage. Compared with handmade spacers or bite blocks, BinkieRT offers distinct advantages in terms of ease of use, hygiene, and reproducibility. The observed immediate dosimetric improvement indicates the potential to reduce the incidence and severity of radiation-induced oral toxicity. Its noninvasive and patient-friendly design also makes it applicable to a wide range of clinical situations, including re-irradiation cases or elderly patients with limited tolerance. BinkieRT provides a simple and practical approach to reduce unnecessary radiation exposure in oral cancer IMRT. Further clinical studies are warranted to validate its efficacy and establish optimal usage protocols.

Indexed as

binkiertimrtintensity-modulated radiation therapyintraoral positioning deviceoral canceroral mucositis prevention

Identifiers

PMID41503305
PMCPMC12770790

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.