Evidence map›Paper›PMID 41503302›Full record

ArticleCureus2025

Reversible Cerebral Vasculopathy Resembling Reversible Cerebral Vasoconstriction Syndrome in a Case of Untreated Basedow's (Graves') Disease.

Miwako Ishikawa, Tomoaki Kameda, Akiko Deguchi, Kazuhiro Saito, Shigeru Fujimoto

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Miwako IshikawaDivision of Neurology, Department of Medicine, Jichi Medical University, Shimotsuke, JPN.
Tomoaki KamedaDepartment of Neurology, Shin-Oyama City Hospital, Oyama, JPN.
Akiko DeguchiDepartment of Diabetes and Endocrinology, Shin-Oyama City Hospital, Oyama, JPN.
Kazuhiro SaitoDivision of Neurology, Department of Medicine, Jichi Medical University, Shimotsuke, JPN.
Shigeru FujimotoDivision of Neurology, Department of Medicine, Jichi Medical University, Shimotsuke, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reversible cerebral vasoconstriction syndrome (RCVS) involves transient, multifocal cerebral artery narrowing. We report the case of a 42-year-old woman presenting with thunderclap headaches one month after thyrotoxicosis onset. Brain computed tomography and magnetic resonance imaging (MRI) were unremarkable, but magnetic resonance angiography (MRA) revealed focal narrowing of the M2 segment of the right middle cerebral artery. Initial treatment with intravenous nicardipine failed to relieve symptoms. After diagnosing Basedow's (Graves') disease and initiating antithyroid therapy, the headaches markedly improved. This case suggests that RCVS may be triggered by thyrotoxicosis alone and that RCVS secondary to Graves' disease may resolve with appropriate antithyroid treatment.

Indexed as

basedow’s diseasemoyamoya vasculopathyreversible cerebral vasoconstriction syndromethunderclap headachethyrotoxicosis

Identifiers

PMID41503302
PMCPMC12773625

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.