Evidence map›Paper›PMID 41503278›Full record

ArticleCase reports in medicine2026

Management of Ablation-Refractory Atrial Fibrillation During Pregnancy.

Faris Abu Za'nouneh, Kevin Benavente, Jadon Neuendorf, Blake Kadomoto, Christina Chong

Abstract read
In one paragraph

Article in Case reports in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Faris Abu Za'nounehDepartment of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, 96813, Hawaii, USA.ORCID https://orcid.org/0000-0002-1216-450X
Kevin BenaventeDepartment of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, 96813, Hawaii, USA.ORCID https://orcid.org/0000-0003-4219-7780
Jadon NeuendorfDepartment of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, 96813, Hawaii, USA.
Blake KadomotoDepartment of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, 96813, Hawaii, USA.
Christina ChongDepartment of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, 96813, Hawaii, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of new atrial fibrillation (AF) is uncommon in pregnancy with an incidence of 0.03%. The occurrence of drug-refractory AF during pregnancy in individuals with structurally normal hearts is even rarer, and there are no reports of ablation-refractory AF during pregnancy in the literature. Early recognition and treatment of AF are crucial, as it causes hemodynamic changes that can adversely impact both the mother and fetus, potentially resulting in poor outcomes. We report a case of a 35-year-old woman at 19 weeks of gestation who presented with recurrent paroxysmal AF. Two years earlier, during her previous pregnancy, she was hospitalized for AF, where she experienced labetalol-related hypotension and failed therapy with verapamil and digoxin. She was then managed with flecainide pill-in-pocket therapy until delivery. Eighteen months before this pregnancy, she underwent catheter ablation and remained stable until this current pregnancy, when she experienced 2 episodes of AF. These episodes were unresponsive to her scheduled regimen, prompting an increase in her beta-blocker dose. However, the patient developed syncope and persistent palpitations prompting her presentation to the emergency department (ED).

Indexed as

ablationantiarrhythmicsatrial fibrillationpregnancyrecurrence

Identifiers

PMID41503278
PMCPMC12771629

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.