Evidence map›Paper›PMID 41503185›Full record

ArticleKidney medicine2026

Repeat Transplantation Rate of Patients Receiving Dialysis After Allograft Nephrectomy.

Steven G Achinger, Juan Carlos Ayus, Ambuj Kumar, Athanasios Tsalatsanis

Abstract read
In one paragraph

Article in Kidney medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Allograft nephrectomy: a systematic review of immunological consequences and management of immunosuppressants.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Steven G AchingerDepartment of Nephrology and Hypertension, University of South Florida, Tampa, FL.
Juan Carlos AyusDepartment of Nephrology, University of California, Irvine, Irvine, CA.
Ambuj KumarResearch Methodology and Biostatistics Core, Office of Research, Department of Internal, Medicine, Morsani College of Medicine, University of South Florida Health, Tampa, FL.
Athanasios TsalatsanisResearch Methodology and Biostatistics Core, Office of Research, Department of Internal, Medicine, Morsani College of Medicine, University of South Florida Health, Tampa, FL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rationale & Objective: Allograft failure has been associated with chronic inflammation and poor survival among dialysis patients after allograft failure. Allograft nephrectomy is associated with higher levels of anti-human alloantibodies, making it more difficult to find matching kidney donors; however, the rate of repeat transplantation following allograft nephrectomy is largely unknown. Study Design: A retrospective, propensity score-matched cohort study. Setting & Participants: Using the US Renal Data System, we identified adult dialysis patients after a failed kidney transplant between January 1, 1995, and December 31, 2015. A total of 50,217 patients met the inclusion criteria. Exposure: Kidney allograft nephrectomy. Outcomes: Primary outcome was repeat kidney transplantation. Analytical Approach: Exposure to nephrectomy was modeled as a time-varying event. We estimated the cumulative incidence of repeat kidney transplant using the competing risk approach. After propensity score matching, 9,696 patients remained in each cohort. Results: Overall, patients with nephrectomy had higher chances of receiving a second transplant (subdistribution HR, 1.21; 95% CI, 1.15-1.28; Limitations: As a retrospective, registry-based study, cause and effect relationship cannot be established. Conclusions: Allograft nephrectomy of a failed kidney allograft is associated with a higher likelihood of repeat transplantation and should not be considered contraindicated in dialysis patients who are candidates for repeat transplantation.

Indexed as

allograft nephrectomychronic inflammationdialysis-free survivalkidney allograft failurerepeat transplantation

Identifiers

PMID41503185
PMCPMC12768901

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.