Evidence map›Paper›PMID 41503167›Full record

ArticleDiabetes epidemiology and management

Characteristics of insulin prescriptions and their association with glycemic control in adults with type 2 diabetes mellitus.

Helen Chen, Lappui Chung, Michael Weiner, Mark Fu, Patrick Balius, Julian Wolfson

Abstract read
In one paragraph

Article in Diabetes epidemiology and management. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Helen ChenDepartment of Epidemiology, Richard Fairbanks School of Public Health, Indiana University, Indianapolis, IN, 46202, USA.
Lappui ChungDivison of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, 55414, USA.
Michael WeinerDepartment of Medicine, School of Medicine, Indiana University, Indianapolis, IN, 46202, USA.
Mark FuDepartment of Computer Science, College of William and Mary, Williamsburg, VA, 23187, USA.
Patrick BaliusDivision of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN, 55414, USA.
Julian WolfsonCenter for Biomedical Informatics, Regenstrief Institute, Inc., Indianapolis, IN, 46202, USA.

Funding

Nurse-led app intervention to improve glycemic control in patients with insulin-treated type 2 diabetes on MedicaidR00NR020377 · NINR · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Helen Nai-Chi Chen · 2025 to 2026
$491k
Improving glycemic control among underserved patients with insulin-treated type 2 diabetes through nurse-led, app-based behavioral interventionK99NR020377 · NINR · INDIANA UNIVERSITY INDIANAPOLIS · PI CHEN, HELEN NAI-CHI · 2023 to 2024
$325k
NINR NIH HHS K99 NR020377NINR NIH HHS L60 NR020964NINR NIH HHS R00 NR020377
6 · The paper itself

Abstract

Objective: We assessed the association between insulin prescription characteristics and glycemic control. Methods: Electronic health records (2017-2023) were used to identify adults with type 2 diabetes prescribed insulin from outpatient visits on the same day as a hemoglobin A1c (HbA1c) result in a Midwest US region. Insulin prescription characteristics were total daily dose, providing a maximum dose, and instruction types (dosing frequency, carbohydrate (carb) counting, correction, and sliding scale). Mixed-effects linear and logistic regression modeled HbA1c and meeting HbA1c target (<7 for age18-64 and <8 for age ≥ 65). Results: Among 11,179 subjects, mean age was 53; 49 % were male, and 58 % White. Overall cohort glycemic control was low, median HbA1c was 9.3; 16 % met HbA1c target; mean HbA1c at last follow-up was 8.7 %. Instruction types were 88 % dosing frequency, 7 % correction, 3 % sliding scale, and 1 % carb counting. HbA1c reduction was associated with carb counting (-0.4, Conclusion: Insulin instruction type was associated with glycemic control, but control was low.

Indexed as

GlycemicHbA1cInsulinPrescriptionsType 2 diabetes

Identifiers

PMID41503167
PMCPMC12774473

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.