ReviewFrontiers in public health2025
Environmental determinants of cerebral haemorrhage in older adults: behavioural pathways and population health implications.
Review in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intracerebral haemorrhage (ICH) is a rapidly fatal cerebrovascular catastrophe that claims a disproportionate share of stroke deaths among older adults despite decades of progress in acute care. Emerging research now implicates a constellation of non-biomedical contextual stressors ambient fine particulate matter, traffic-derived gases and noise, thermal volatility, and bio-accumulative heavy metals, themselves patterned by social determinants of health and political-commercial decision-making as pivotal but still under-recognised drivers of small-vessel rupture. This review synthesises epidemiological, behavioural and translational evidence to illuminate how pollutant-driven sympathetic arousal, sleep fragmentation, physical inactivity and impaired thermoregulation converge on age-accentuated endothelial fragility, thereby lowering the haemodynamic threshold for cerebral bleeding. We further map the geo-temporal and socio-spatial inequities in these exposures rooted in social, political and commercial determinants of health that tether disadvantaged communities to higher exposure loads and outline the corresponding gradients in ICH incidence, mortality and disability-adjusted life-years. We appraise the preventive leverage of integrated structural policies that decarbonise urban transport, regulate commercial determinants, dampen nocturnal noise, expand equitable green infrastructure and fortify climate resilience. By advancing a behavioural-environmental framework that links modifiable exposures to actionable pathways, this article furnishes clinicians, public-health practitioners and policymakers with a coherent agenda for mitigating the impending surge of environmentally mediated cerebral haemorrhage in ageing societies.
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