ArticlebioRxiv : the preprint server for biology2025
Retinal Origins of Circadian Photoregulation's Specialized Dynamic Range and Temporal Integration.
Elliott S Milner, Hannah A Blume, S Navid Mousavi, Michael C Brown, Franklin Caval-Holme, Nguyen-Minh Viet, Takeharu Nagai, Michael Tri H Do
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Elliott S MilnerF. M. Kirby Neurobiology Center and Department of Neurology, Boston Children's Hospital and Harvard Medical School.
Hannah A BlumeF. M. Kirby Neurobiology Center and Department of Neurology, Boston Children's Hospital and Harvard Medical School.
S Navid MousaviF. M. Kirby Neurobiology Center and Department of Neurology, Boston Children's Hospital and Harvard Medical School.
Michael C BrownF. M. Kirby Neurobiology Center and Department of Neurology, Boston Children's Hospital and Harvard Medical School.
Franklin Caval-HolmeF. M. Kirby Neurobiology Center and Department of Neurology, Boston Children's Hospital and Harvard Medical School.
Nguyen-Minh VietF. M. Kirby Neurobiology Center and Department of Neurology, Boston Children's Hospital and Harvard Medical School.
Takeharu NagaiGraduate School of Frontier Biosciences, The University of Osaka.
Michael Tri H DoF. M. Kirby Neurobiology Center and Department of Neurology, Boston Children's Hospital and Harvard Medical School.ORCID 0000-0001-6418-0977 Funding
Viral ModuleP30EY012196 · NEI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ZHIGANG HE · 1998 to 2026
$21.3MMouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI POMEROY, SCOTT LOREN · 2016 to 2020
$5.2MProperties and Mechanisms of Melanopsin PhotoreceptionR01EY023648 · NEI · BOSTON CHILDREN'S HOSPITAL · PI DO, MICHAEL TRI HOANG · 2013 to 2022
$4.5MIntrinsically photosensitive retinal ganglion cells and their central projectionsR01EY025555 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DO, MICHAEL TRI HOANG, GAMLIN, PAUL DOUGLAS · 2016 to 2020
$3.9MDownstream Actions of Biophysical Mechanisms in the Visual System-Diversity SupplementR01EY034089 · NEI · BOSTON CHILDREN'S HOSPITAL · PI Michael Tri Hoang Do · 2022 to 2026
$3.0MSignal Generation and Processing in the Retinohypothalamic PathwayR01EY036071 · NEI · BOSTON CHILDREN'S HOSPITAL · PI Michael Tri Hoang Do · 2024 to 2026
$2.1MNeurophysiology of Melanopsin PhotoreceptorsR01EY036430 · NEI · BOSTON CHILDREN'S HOSPITAL · PI Michael Tri Hoang Do · 2024 to 2026
$1.7MOrigins and Transformations of Signals for Circadian RegulationR21EY032731 · NEI · BOSTON CHILDREN'S HOSPITAL · PI DO, MICHAEL TRI HOANG · 2021 to 2022
$617kTransformations of photic information in melanopsin pathwaysK99EY037374 · NEI · BOSTON CHILDREN'S HOSPITAL · PI Franklin Caval-Holme · 2025 to 2026
$273kSubcellular Origins of Extensive Spatial Integration by Ganglion Cell PhotoreceptorsF32EY033639 · NEI · BOSTON CHILDREN'S HOSPITAL · PI CAVAL-HOLME, FRANKLIN · 2022 to 2024
$213kPhysiological Mechanisms of Intensity Encoding in Ganglion Cell PhotoreceptorsF31EY025466 · NEI · HARVARD MEDICAL SCHOOL · PI MILNER, ELLIOTT SCOTT · 2015 to 2017
$95kNEI NIH HHS F31 EY025466NEI NIH HHS F32 EY033639NEI NIH HHS K99 EY037374NEI NIH HHS P30 EY012196NEI NIH HHS R01 EY023648NEI NIH HHS R01 EY025555NEI NIH HHS R01 EY034089NEI NIH HHS R01 EY036071NEI NIH HHS R01 EY036430NEI NIH HHS R21 EY032731NICHD NIH HHS U54 HD090255
6 · The paper itselfAbstract
The circadian clock allows organisms to anticipate environmental changes that are driven by the earth's rotation, and synchronizes with this cycle using light
Identifiers
PMID41502948
PMCPMC12773001
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