Evidence map›Paper›PMID 41502930›Full record

ArticlebioRxiv : the preprint server for biology2026

Meta-learning is expressed through altered prefrontal cortical dynamics.

Xulu Sun, Alison E Comrie, Ari E Kahn, Emily J Monroe, Clayton B Washington, Abhilasha Joshi, Jennifer A Guidera, Eric L Denovellis, Timothy A Krausz, Jenny Zhou and 8 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Xulu SunDepartment of Physiology and Psychiatry, University of California, San Francisco; San Francisco, CA 94158, USA.ORCID 0000-0003-3076-0994
Alison E ComrieDepartment of Physiology and Psychiatry, University of California, San Francisco; San Francisco, CA 94158, USA.ORCID 0000-0002-2251-4892
Ari E KahnPrinceton Neuroscience Institute, Princeton University; Princeton, NJ 08544, USA.ORCID 0000-0002-2127-0507
Emily J MonroeDepartment of Physiology and Psychiatry, University of California, San Francisco; San Francisco, CA 94158, USA.
Clayton B WashingtonCenter for Machine Learning and Department of Biomedical Engineering, Georgia Institute of Technology and Emory University; Atlanta, GA 30322, USA.
Abhilasha JoshiHoward Hughes Medical Institute; Chevy Chase, MD 20815, USA.ORCID 0000-0002-0511-3747
Jennifer A GuideraMedical Scientist Training Program, University of California, San Francisco; San Francisco, CA 94143, USA.ORCID 0000-0003-4013-214X
Eric L DenovellisHoward Hughes Medical Institute; Chevy Chase, MD 20815, USA.ORCID 0000-0003-4606-087X
Timothy A KrauszNeuroscience Graduate Program, University of California San Francisco; San Francisco, CA 94158, USA.ORCID 0000-0002-9561-8641
Jenny ZhouCenter for Micro- and Nano-Technology, Lawrence Livermore National Laboratory; Livermore, 94550, USA.
Paige ThompsonCenter for Micro- and Nano-Technology, Lawrence Livermore National Laboratory; Livermore, 94550, USA.
Jose HernandezCenter for Micro- and Nano-Technology, Lawrence Livermore National Laboratory; Livermore, 94550, USA.
Allison YoritaCenter for Micro- and Nano-Technology, Lawrence Livermore National Laboratory; Livermore, 94550, USA.
Razi HaqueCenter for Micro- and Nano-Technology, Lawrence Livermore National Laboratory; Livermore, 94550, USA.
Chethan PandarinathCenter for Machine Learning and Department of Biomedical Engineering, Georgia Institute of Technology and Emory University; Atlanta, GA 30322, USA.ORCID 0000-0003-1241-1432
Joshua D BerkeKavli Institute for Fundamental Neuroscience, University of California, San Francisco; San Francisco, CA 94158, USA.ORCID 0000-0003-1436-6823
Nathaniel D DawPrinceton Neuroscience Institute, Princeton University; Princeton, NJ 08544, USA.ORCID 0000-0001-5029-1430
Loren M FrankDepartment of Physiology and Psychiatry, University of California, San Francisco; San Francisco, CA 94158, USA.ORCID 0000-0002-1752-5677

Funding

Value networks and hippocampal non-local representationsR01MH136875 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOSHUA D BERKE, Nathaniel Douglass Daw · 2024 to 2026
$2.4M
Differentiating reward seeking and loss avoidance with reference-dependent learning modelsR01MH121093 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI DAW, NATHANIEL DOUGLASS, SHOHAMY, DAPHNA · 2019 to 2022
$2.1M
Investigating neural substrates of generalization from past experienceF30MH126483 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GUIDERA, JENNIFER ANN · 2021 to 2024
$150k
Hippocampal-cortical interactions supporting memory and value-guided decision-makingF31MH124366 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COMRIE, ALISON E. · 2020 to 2022
$123k
NIMH NIH HHS F30 MH126483NIMH NIH HHS F31 MH124366NIMH NIH HHS R01 MH121093NIMH NIH HHS R01 MH136875
6 · The paper itself

Abstract

Learning where and when rewards like food and water are available is essential for survival

Identifiers

PMID41502930
PMCPMC12772998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.