ArticleTranslational pediatrics2025
Sclerosing perineurioma of the anterior chest wall in an active Caucasian toddler: a case report.
Article in Translational pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Perineurioma is a rare benign tumor of the peripheral nerve sheath, encompassing intraneural, traditional soft tissue, reticular, and sclerosing variants. Sclerosing perineurioma is a rare variation that predominantly manifests on the hands of young adults, presenting as a tiny, painless subcutaneous tumor. The incidence of pediatric perineurioma is very low, with only a few dozen cases reported in the literature. The primary cause for appointments at the outpatient clinic is a gradually enlarging asymptomatic tumor. The affected areas usually include the thumb (acral location). The lesions are typically solid, well-defined white masses with a fibrous texture, measuring 1.2-4.0 cm in maximum dimension. Case Description: We present a 2-year-6-month-old male with a sclerosing perineurioma of the left anterior chest wall and delineate the lesion's ultrasonographic and pathological characteristics. Conclusions: This case report illustrates an almost unique pediatric instance of sclerosing perineurioma of the left anterior chest with additional, previously unreported imaging progression since birth. This case report is critical for general pediatrics and pediatric radiology. A description of this case aids in diagnosing extra-acral features of this tumor. Moreover, this case report may improve understanding of the imaging-pathology correlation of this tumor, benefiting both specialists and fellows.
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