Evidence map›Paper›PMID 41502716›Full record

ArticleACS omega2025

Photothermic Release of Curcumin for Antimicrobial Photodynamic Therapy.

Jeffersson K Trigo-Gutierrez, Serena Medaglia, Elena Aznar, Ramón Martínez-Máñez, Ewerton G O Mima

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jeffersson K Trigo-GutierrezUniversidad Privada Franz Tamayo, Facultad de Ciencias de la Salud, Carrera de Odontología, sede La Paz 1855, Bolivia.ORCID https://orcid.org/0000-0002-1004-2429
Serena MedagliaInstituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de Valencia, Universitat de València, 46022 Valencia, Spain.ORCID https://orcid.org/0000-0003-3537-9842
Elena AznarInstituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de Valencia, Universitat de València, 46022 Valencia, Spain.ORCID https://orcid.org/0000-0003-0361-3876
Ramón Martínez-MáñezInstituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de Valencia, Universitat de València, 46022 Valencia, Spain.ORCID https://orcid.org/0000-0001-5873-9674
Ewerton G O MimaDepartment of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University (Unesp), Araraquara, São Paulo 14801-903, Brazil.ORCID https://orcid.org/0000-0002-9575-7625

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug delivery systems (DDS) are promising tools to enhance antimicrobial Photodynamic Therapy (aPDT) by improving the targeted delivery and controlled release of photosensitizers. In this study, we introduce a light-responsive DDS based on curcumin-loaded mesoporous silica nanoparticles featuring a gold nanostar core and paraffin capping, designed specifically for near-infrared (NIR)-triggered photothermal release. This multicomponent nanoplatform uniquely combines photothermal activation with light-controlled drug delivery for antimicrobial applications. The synthesized nanoparticles exhibited a mean diameter below 500 nm, a polydispersity index of 0.154, and a surface charge of -21.9 mV. Upon NIR irradiation at 1200 J/cm

Identifiers

PMID41502716
PMCPMC12771119

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.