ArticleACS omega2025
Cu-Gallate MOF-Chitosan Hybrid Membrane for Low-Power, Non-Invasive Acetone Sensing: Toward Early-Stage Diabetes Detection.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The precise and noninvasive detection of volatile organic compounds (VOCs) is of growing importance in medical diagnostics, health monitoring, and environmental assessment. Among these VOCs, acetone in human breath serves as a key biomarker for the early detection of diabetes. In this work, we report the development of a high-performance composite membrane sensor based on a copper gallate metal-organic framework (Cu-gallate MOF) integrated with chitosan (CS) and doped with ionic liquid glycerol (IL). The incorporation of chitosan significantly improved membrane conductivity and structural stability, while hydrogen-bonding interactions enhanced acetone selectivity. As a result, the Cu-gallate MOF/CS/IL sensor achieved a remarkable detection limit of 0.25 ppm at an operating temperature of 80 °C, with rapid response (27 s) and recovery (10 s) times. The sensor further demonstrated excellent selectivity, long-term durability, and reproducible performance under practical testing conditions. These findings highlight the potential of MOF-based mixed-matrix membranes as a cost-effective and energy-efficient platform for real-time breath analysis, providing a promising pathway toward early diagnosis and monitoring of diabetes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.