ArticleACS omega2025
Tailoring Graphene Oxide-Infused Hydroxyapatite Coatings on Titanium: Electrochemical Insights and Simulation for Enhanced Bone Implant Performance.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Hydroxyapatite-based bone repair biomaterials based on clinical heterogeneity: modification strategies, performance regulation, and personalized repair pathways.Frontiers in bioengineering and biotechnology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inspired by the self-healing capabilities of skeletal tissues, advanced osteoinductive treatments, such as calcium phosphate ceramics, have been developed to improve bone repair. Hydroxyapatite (HAP), renowned for its osteoconductive and osteoinductive properties, is commonly used in dental and orthopedic implants. However, HAP's mechanical limitations under load-bearing conditions drive the need for composites that incorporate reinforcing materials. Graphene, with its superior surface area, conductivity, mechanical strength, and biocompatibility, is an ideal candidate for enhancing HAP composites. This study explores the development of graphene oxide (GO)-based nano HAP (n-HAP/GO) composite coating via electrophoretic deposition (EPD) on titanium (Grade-2) surfaces, optimizing deposition voltages (60-90 V) and time (3 min) to achieve uniform, adherent, and crack-free coatings. Various characterization techniques, including high-resolution transmission electron microscopy (HR-TEM), high-resolution scanning electron microscopy (HR-SEM), optical microscope, contact angle measurement, and electrochemical analyses (open circuit potential (OCP), potentiodynamic polarization, and electrochemical impedance spectroscopy (EIS)), were employed to assess morphology, bioactivity, and corrosion resistance. Results indicate that coatings deposited at 80 V for 3 min exhibited better characteristics including reduced porosity, enhanced hydrophilicity, and improved corrosion resistance, which records the highest corrosion potential (
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Registered trials
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