ArticleACS omega2025
Lectin-Coated Silver/Silver Chloride Nanoparticles in Combination with Gentamicin: A Strategy to Preserve Antibiotic Efficacy at Lower Doses Against Pathogenic Planktonic Bacteria.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The rampant overuse of antibiotics in recent decades has significantly contributed to the emergence of antibiotic resistance. This highlights the need for new antibacterial strategies to reduce dependence on traditional antibiotics and slow the development of resistance. Concanavalin A-coated silver/silver chloride nanoparticles (ConA/Ag/AgCl-NPs) offer a promising alternative, combining the antimicrobial activity of metallic silver with the ability of concanavalin A to interact with both membrane carbohydrates and antibiotic gentamicin. The aim of this study is to investigate the synergistic antibacterial activity of gentamicin combined with ConA/Ag/AgCl-NPs against pathogenic bacteria. Our results confirmed that gentamicin interacts with ConA/Ag/AgCl-NPs, altering their plasmonic resonance properties. The combination of gentamicin with ConA/Ag/AgCl-NPs significantly reduced the minimum inhibitory concentration (MIC) values of both, from 0.19 μg/mL and 0.04 μg/mL to 0.02 μg/mL and 0.01 μg/mL, respectively, required to inhibit planktonic
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.