Evidence map›Paper›PMID 41502562›Full record

ArticleResearch square2026

Prevalence and associated factors of unilateral spatial neglect among patients with stroke at Mbarara Regional Referral Hospital, Uganda: a cross-sectional study.

Asiimwe Derrick, Migisha Richard, Nuwahereza Amon, Nkoyooyo Dauglaus, Lubwama Conrad, Namayanja Rosemary, Omolo Ouma Ronald, Martha Sajatovic, Josephine Najjuma, Mark Kaddumukasa and 3 more

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In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Asiimwe DerrickDepartment of Physiology, Mbarara University of Science and Technology, Mbarara, Uganda.
Migisha RichardDepartment of Physiology, Mbarara University of Science and Technology, Mbarara, Uganda.
Nuwahereza AmonDepartment of Physiotherapy, Mbarara Regional Referral Hospital, Mbarara, Uganda.
Nkoyooyo DauglausDepartment of Physiology, Mbarara University of Science and Technology, Mbarara, Uganda.
Lubwama ConradDepartment of Physiology, Mbarara University of Science and Technology, Mbarara, Uganda.
Namayanja RosemaryDepartment of Physiology, Mbarara University of Science and Technology, Mbarara, Uganda.
Omolo Ouma RonaldDepartment of Physiology, Mbarara University of Science and Technology, Mbarara, Uganda.
Martha SajatovicDepartment of Psychiatry and Neurology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Josephine NajjumaDepartment of Nursing, Mbarara University of Science and Technology, Mbarara, Uganda.
Mark KaddumukasaDepartment of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Elly KatabiraDepartment of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Kira BullockDepartment of Neurology, Duke Global Neurosurgery & Neurology, Duke University, Durham, North Carolina, USA.
Agaba David CollinDepartment of Physiology, Mbarara University of Science and Technology, Mbarara, Uganda.

Funding

A Targeted Self-Management Intervention for Reducing Stroke Risk Factors in High Risk UgandansR01NS118544 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI KATABIRA, ELLY T, SAJATOVIC, MARTHA X · 2020 to 2025
$3.0M
NINDS NIH HHS R01 NS118544
6 · The paper itself

Abstract

Background: Unilateral spatial neglect (USN) is a common neurocognitive deficit following stroke. It impairs rehabilitation and functional outcomes, particularly in low-resource settings where data are limited. This study determined the prevalence of USN and its associated factors among patients with stroke at Mbarara Regional Referral Hospital (MRRH), southwestern Uganda. Methods: We conducted a cross-sectional study from August 12 to December 15, 2024. Patients with a recent stroke event within the preceding 0-4 months receiving care at MRRH were enrolled using consecutive sampling. Patients who were unable to see or were aged <18 years were excluded. USN was assessed using the Sunnybrook Neglect Assessment Procedure (SNAP): scores >5 indicating USN. Sociodemographic, clinical, and lifestyle factors were collected via structured questionnaires. Multivariable modified Poisson regression was used to identify factors associated with USN, reporting adjusted prevalence ratios (aPR) with 95% confidence intervals (CI). Results: We enrolled 117 participants with a median age of 68 years (interquartile range [IQR]: 56-78). Most were female (65.8%). The prevalence of USN was 53.8% (n=63; 95% CI: 44-63). USN was more prevalent in the acute phase (60%) compared to the subacute (32%) and chronic phases (8%). Factors significantly associated with USN included severe stroke (aPR=1.47, 95% CI: 1.12-1.92, p=0.005), right-hemisphere lesions (aPR=1.58, 95% CI: 1.14-2.19, p=0.006), age ≥60 years (aPR=1.66, 95% CI: 1.02-2.72, p=0.042), and right-handedness (aPR=0.94, 95% CI: 0.94-0.99, p<0.001). \. Conclusion: This study revealed a high prevalence of USN among patients with stroke at a referral hospital in southwestern Uganda. Stroke severity, right-hemisphere lesions, advanced age, and right-handedness were associated with USN. Targeted rehabilitation and early screening for patients with stroke with risk factors, particularly those with severe strokes or advanced age, could optimize recovery and improve long-term outcomes.

Indexed as

cerebrovascular disordersprevalencestrokeStroke rehabilitationUgandaUnilateral spatial neglect

Identifiers

PMID41502562
PMCPMC12772689

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.