ReviewBiomaterial investigations in dentistry2026
BioHPP in prosthetic dentistry: a narrative review of mechanical, biological, and clinical properties.
Review in Biomaterial investigations in dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Immediate Loading of 5.2-mm Ultra-Short Implants Supporting Maxillary Overdentures in the Severely Atrophic Maxilla: A Prospective Pilot Study.Journal of clinical medicine · 2026Article
- Effects of Ultrasonic Scaling and Teeth Brushing on Surface Properties of PEEK Prosthetic Restorations.Dentistry journal · 2026Article
- Effect of Alumina Airborne-Particle Abrasion Followed by Plasma Treatment on Bond Strength of Dental PEEK to MMA-Based Luting Systems.Bioengineering (Basel, Switzerland) · 2026Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biocompatible high-performance polymer (BioHPP), a high-performance polymer derived from polyetheretherketone (PEEK) and reinforced with ceramic fillers, has emerged as a promising alternative to conventional metal and ceramic framework materials in prosthetic dentistry. With an elastic modulus (~4 GPa) comparable to that of cortical bone, BioHPP promotes physiological stress distribution and reduces stress shielding, thereby supporting peri-implant bone preservation. Its excellent chemical inertness and low bacterial affinity minimize mucosal inflammation and reduce the risk of peri-implant disease. However, the material's low surface energy and hydrophobicity pose challenges to long-term adhesive stability, necessitating specific surface modification techniques and specialized adhesive systems. Clinically, BioHPP has been successfully applied in single crowns, fixed partial dentures, full-arch hybrid prostheses (e.g. All-on-Four), bar-retained overdentures, maxillofacial frameworks, customized abutments, and provisional restorations. Despite its favorable biomechanical and biological profile, limitations such as inherent opacity, restricted fracture toughness, and the scarcity of long-term clinical data highlight the need for further interdisciplinary research and material innovation. This narrative review comprehensively evaluates the mechanical, biological, and adhesive characteristics of BioHPP, compares its performance with traditional framework materials, and discusses its clinical applications and future perspectives in prosthetic rehabilitation.
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Registered trials
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