Health economic analysis of seizure-related emergency visits of pediatric patients with drug-resistant epilepsy in Japan.

Ayataka Fujimoto, Takuya Kumagai, Kazuaki Yamamoto, Katsuhiko Iwasaki, Kinya Kokubo, Ataru Igarashi

Abstract read

In one paragraph

Article in Epilepsy & behavior reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ayataka FujimotoEpilepsy and Functional Neurosurgery, Department of Neurosurgery, Dokkyo Medical University School of Medicine, Tochigi, Japan.

Takuya KumagaiAculys Pharma, Inc., Tokyo, Japan.

Kazuaki YamamotoHealthcare Consulting, Inc., Tokyo, Japan.

Katsuhiko IwasakiHealthcare Consulting, Inc., Tokyo, Japan.

Kinya KokuboHealthcare Consulting, Inc., Tokyo, Japan.

Ataru IgarashiGraduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study estimates the cost of emergency transport and the total cost of medical care for pediatric patients with drug-resistant epilepsy (DRE) in Japan. We perform a retrospective analysis of patients aged less than 18 years with DRE. We use a health insurance claims database to identify the patients. The data are combined with published information, including government statistics and prior studies. We calculate the median medical cost for these patients after emergency and the cost per emergency transport service using recent data published by the Fire and Disaster Management Agency and calculation logic. The cost per emergency transport service is approximately 138,600 yen. Additionally, the cost of emergency transport for pediatric patients with DRE and the total medical cost in Japan are approximately 511,949,800 and 597,536,619 yen per year, respectively. This study is among the first to estimate the annual costs of seizure-related emergency transport and medical care for pediatric patients with DRE in Japan. These estimates can serve as baseline data for use in future assessments of the cost-effectiveness of acute medical care in this population.

Indexed as

Emergency transport costsHealth insurance claims databasePediatric drug-resistant epilepsyTotal medical costs

Identifiers

PMID41502451

DOI10.1016/j.ebr.2025.100840

PMCPMC12768918

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.