Evidence map›Paper›PMID 41502107›Full record

ArticleInternational journal of stroke : official journal of the International Stroke Society2026

Stroke patterns, risk factors, management, and outcomes from hospital-based stroke registries in India.

Prashant Mathur, Deepadarshan Huliyappa, Prathyusha Pv, Vinay Urs, Rahul Rajendra Koli, Sureshkumar N, Kavyashree Seenappa, National Stroke Registry Programme (NSRP) Investigators

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Article in International journal of stroke : official journal of the International Stroke Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Prashant MathurICMR-National Centre for Disease Informatics and Research, Bengaluru, India.ORCID 0000-0002-9271-1373
Deepadarshan HuliyappaICMR-National Centre for Disease Informatics and Research, Bengaluru, India.ORCID 0000-0002-3382-9101
Prathyusha PvICMR-National Centre for Disease Informatics and Research, Bengaluru, India.
Vinay UrsICMR-National Centre for Disease Informatics and Research, Bengaluru, India.ORCID 0000-0002-7317-4429
Rahul Rajendra KoliICMR-National Centre for Disease Informatics and Research, Bengaluru, India.
Sureshkumar NICMR-National Centre for Disease Informatics and Research, Bengaluru, India.
Kavyashree SeenappaICMR-National Centre for Disease Informatics and Research, Bengaluru, India.
National Stroke Registry Programme (NSRP) InvestigatorsICMR-National Centre for Disease Informatics and Research, Bengaluru, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndia is facing a growing burden of stroke due to population aging, lifestyle changes, and increased exposure to risk factors. However, longitudinal data on stroke patterns and outcomes in India are limited.

objectivesThis study assessed stroke patterns, risk factors, management practices, and outcomes using data from the Hospital-Based Stroke Registries (HBSRs) in India.

methodsThis prospective hospital-based registry included 34,792 stroke cases from 30 centers across India, recorded between 2020 and 2022. Data on demographics, clinical features, risk factors, diagnostics, treatments, and outcomes were collected, with follow-up at 28 days and 3 months. Functional outcome was assessed using the modified Rankin Scale (mRS), along with data on recurrence.

resultsThe mean age was 59.4 years; 13.8% were aged under 45, 63.4% were male, and 72.1% were from rural areas. Hypertension (74.5%) was the most common risk factor, followed by smokeless tobacco use (28.5%) and diabetes mellitus (27.3%). Ischemic stroke accounted for 60% of cases. Only 20.1% were presented within 4.5 h of symptom onset, while 37.8% of cases presented after 24 h. Motor impairment (74.8%) followed by speech disturbance (51.2%) were the commonest symptoms at onset. Thrombolysis was given in 4.6%, and thrombectomy in 0.7%, of ischemic strokes. At 3 months, 27.8% had died, 29.7% had significant disability (mRS 3-5), and 1.1% had a recurrent stroke.

conclusionIn this study, one in 7 stroke were in the young, 2 in 5 patients arrived after 24 h of symptom onset, and thrombolysis and mechanical thrombectomy were underutilized. Over half had poor 3-month outcomes, highlighting the need for improving comprehensive stroke care across India.

Indexed as

StrokeAdultAgedFemaleHumansIndiaMaleMiddle AgedProspective StudiesRegistriesRisk FactorsTreatment OutcomeIndiarisk factorsstroke outcomesstroke registry

Identifiers

PMID41502107
PMCPMC13291390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.