ArticleBMC genomics2026
Epididymal transcriptional networks underlying sperm motility differences in Chinese indigenous chicken breeds.
Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Improvement of cryopreserved rooster semen quality by combined application of DMF and ZnO NPs.Poultry science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
This study characterized phenotypic distinctions between high- and low-motility sperm from 40-week-old Yufen1 roosters and the alteration in epididymal transcriptional networks underlighting sperm motility. Temperature challenge tests (4 °C and 37 °C) revealed that high-viability sperm maintained significantly better survival rates at both temperatures compared to low-viability samples, and high-motility sperm consistently exhibited lower morphological abnormality rates across temperature conditions (P < 0.05), which was further confirmed by extended fertilization windows (P < 0.05) and produced more fertilized eggs (P < 0.05) compared to the low-motility group. Transcriptomic analysis of the epididymis showed 723 differentially expressed genes between the low- and high- motility groups, with functional enrichment indicating significant alterations in lipid metabolism pathways and ATP synthesis-related processes. Accordingly, genes related to fat deposition such as acyl-CoA synthetase bubblegum family member 1 (ACSBG1), glycerate kinase (GLYCTK), and CDP-diacylglycerol synthase 1 (CDS1) were downregulated (all P < 0.05), whereas the mRNA level of β-oxidation gene acyl-coenzyme A thioesterase 6 (ACOT6) was increased (P < 0.05) in the high motility group as compared to the low motility group. In addition, when compared to the low motility group, the high motility semen exhibited decreased levels of both reactive oxygen species (ROS) and malondialdehyde in seminal plasma (both P < 0.05). In conclusion, the maintenance of sperm motility is associated with lipid metabolism remodeling, where these metabolic adaptations enhance ATP production while simultaneously reducing ROS generation in Yufen1 roosters.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.