Evidence map›Paper›PMID 41501562›Full record

ArticleNeuroinformatics2026

Revealing Structural Brain-Cognition Relationships in Children: A Comparison of Morphometric Similarity and INverse Divergence Networks.

Shuning Han, Hao Jia, Gemma Vilaseca, Núria Vilaró, Feng Duan, Zhe Sun, Cesar F Caiafa, Jordi Solé-Casals

Abstract readComparative Study
In one paragraph

Article in Neuroinformatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shuning HanData and Signal Processing Research Group, University of Vic-Central University of Catalonia, Vic, Catalonia, 08500, Spain.
Hao JiaSchool of Medicine, Nankai University, Tianjin, 300355, China.
Gemma VilasecaPsychological Department, Oms and Prat school, Fundació Catalunya - La Pedrera, Manresa, Catalonia, 08243, Spain.
Núria VilaróOms Foundation, Manresa, Catalonia, 08243, Spain.
Feng DuanSchool of Medicine, Nankai University, Tianjin, 300355, China.
Zhe SunFaculty of Health Data Science, Juntendo University, Urayasu, Chiba, 279-0013, Japan.
Cesar F CaiafaInstituto Argentino de Radioastronomía-CCT La Plata, CONICET / CIC-PBA / UNLP, V. Elisa, 1894, Argentina.
Jordi Solé-CasalsData and Signal Processing Research Group, University of Vic-Central University of Catalonia, Vic, Catalonia, 08500, Spain. jordi.sole@uvic.cat.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study of structural brain networks (SBNs) offers critical insights into brain-cognition relationships. However, a comprehensive comparison of these methods in terms of their topological properties, cognitive relevance, and sensitivity to connection density remains lacking. This study compares two types of individual-level SBNs-morphometric similarity networks (MSNs) and morphometric inverse divergence (MIND) networks-by analyzing their associations with cognitive performance using sMRI data from 29 male children. Group- and individual-level analyses were conducted to evaluate differences in hemispheric connectivity, topological features, and their correlations with cognitive performance across different connection densities. In our analyses, a connection density of [Formula: see text] appeared optimal for stabilizing network properties and maximizing cognitive correlations in both MSN and MIND. Moreover, advanced network segregation and integration metrics (such as local efficiency and node versatility, along with their global summaries) demonstrated greater sensitivity to cognitive performance. However, MSNs appeared to provide a more reliable framework, demonstrating more stable associations across connection densities in topological and hemispheric dimensions. Specifically, higher cognitive performance may be linked to stronger left intra-hemispheric connectivity, weaker inter-hemispheric connectivity, and more modular network organization-consistent with established theories of hemispheric specialization and efficient modularity. In contrast, MIND networks exhibit reduced effectiveness and stability across metrics and densities in our data. These preliminary insights enhance our understanding of brain-cognition relationships and provide practical guidelines for parameter selection and metric identification in network-based cognitive analyses.

Indexed as

BrainCognitionNerve NetBrain MappingChildHumansMagnetic Resonance ImagingMaleNeural PathwaysGifted childrenHemispheric connectivityMorphometric INverse divergenceMorphometric similarity networkStructural magnetic resonance imagingTopological features

Identifiers

PMID41501562
PMCPMC12779738

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.