Evidence map›Paper›PMID 41501407›Full record

ArticlePediatric research2026

Whole-body hypothermia in late preterm and early term infants: a retrospective analysis from a neurocritical care unit.

Alejandra Martinez, Gokalp Cikman, Heeba Al Kalaf, Diane Wilson, Benjamin Banh, Wael Abdelmageed, Ignacio Beamonte Arango, Rhandi Christensen, Helen M Branson, Mehmet N Cizmeci

Abstract read
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Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alejandra MartinezThe Hospital for Sick Children, and Department of Paediatrics, University of Toronto, Toronto, Canada.
Gokalp CikmanDepartment of Diagnostic Imaging and Interventional Radiology, The Hospital for Sick Children, and Department of Medical Imaging, University of Toronto, Toronto, Canada.
Heeba Al KalafDivision of Neurology, The Hospital for Sick Children, and Department of Paediatrics, University of Toronto, Toronto, Canada.
Diane WilsonDivision of Neonatology, The Hospital for Sick Children, and Department of Paediatrics, University of Toronto, Toronto, Canada.
Benjamin BanhDivision of Neonatology, The Hospital for Sick Children, and Department of Paediatrics, University of Toronto, Toronto, Canada.
Wael AbdelmageedDivision of Neonatology, The Hospital for Sick Children, and Department of Paediatrics, University of Toronto, Toronto, Canada.
Ignacio Beamonte ArangoDivision of Neonatology, The Hospital for Sick Children, and Department of Paediatrics, University of Toronto, Toronto, Canada.
Rhandi ChristensenDivision of Neurology, The Hospital for Sick Children, and Department of Paediatrics, University of Toronto, Toronto, Canada.
Helen M BransonDepartment of Diagnostic Imaging and Interventional Radiology, The Hospital for Sick Children, and Department of Medical Imaging, University of Toronto, Toronto, Canada.
Mehmet N CizmeciDivision of Neonatology, The Hospital for Sick Children, and Department of Paediatrics, University of Toronto, Toronto, Canada. mehmet.cizmeci@sickkids.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare the outcomes of whole-body hypothermia (WBH) in infants with neonatal encephalopathy born at 34

methodsRetrospective analysis of 122 outborn infants in a single unit: Group 1 (n = 63; 34

resultsGroup 1 had more hemodynamic instability (67% vs. 32%, p < 0.001), hypoglycemia (54% vs 36%, p = 0.04), and higher white-matter and total brain-injury scores (medians 7 vs. 4 and 10 vs. 5, both p ≤ 0.05), compared with Group 2. Overall mortality was 22% (14/63) vs. 12% (7/59), respectively (adjusted odds ratio [aOR] 3.49, 95% CI 1.06-11.50). Composite outcome of death or moderate-severe neurodevelopmental impairment (NDI) was more common in Group 1 (42% vs. 21%; aOR 2.94, 95% CI 1.02-8.46). The 35

conclusionAt 34 IMPACT: Late preterm infants born at 34

Indexed as

Hypothermia, InducedInfant, PrematureFemaleGestational AgeHemodynamicsHumansHypoglycemiaInfantInfant, NewbornMaleNeurodevelopmentRetrospective StudiesTreatment Outcome

Identifiers

PMID41501407

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.