ReviewNature cell biology2026
Structural organization and function of telomeric chromatin.
Review in Nature cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- How telomere attrition protects against cancer.Nature reviews. Genetics · 2026Review
- Single-molecule variation in telomeric sequence and structure across humans.bioRxiv : the preprint server for biology · 2026Article
- Nucleosome spacing across cell types, diseases, and ages.Nucleic acids research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Telomeres were originally classified as constitutive heterochromatin, an inert chromatin state characteristic of repetitive regions. However, this view has been increasingly challenged by analyses of the epigenetic signature and molecular behaviour of human telomeric chromatin. Recent structural and genetic studies further highlight the distinctive and dynamic nature of the telomeric architecture. Here we present an updated perspective on telomeric chromatin, focusing on the unique features that set telomeres apart from other genomic regions and that equip them to address the specific challenges at chromosome ends. In addition, we discuss how alterations in telomeric chromatin influence stem cells, inherited diseases and cancer, demonstrating how telomere architecture governs both its integrity and function.
Indexed as
Identifiers
41501176What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.