Evidence map›Paper›PMID 41500977›Full record

ReviewParasite immunology2026

Mechanisms of Immune Evasion, Dissemination, and Persistence in Leishmania amazonensis Infection.

Arieli Bernardo Portugal, Renato Augusto DaMatta, Edézio Ferreira da Cunha Júnior, João Luiz Mendes Wanderley

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Parasite immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arieli Bernardo PortugalLaboratório de Imunoparasitologia, Instituto de Ciências Médicas, Universidade Federal do Rio de Janeiro, Macaé, Brazil.
Renato Augusto DaMattaLaboratório de Biologia Celular e Tecidual, Universidade Estadual Norte Fluminense (UENF), Campos dos Goytacazes, Rio de Janeiro, Brazil.
Edézio Ferreira da Cunha JúniorLaboratório de Imunoparasitologia, Instituto de Ciências Médicas, Universidade Federal do Rio de Janeiro, Macaé, Brazil.
João Luiz Mendes WanderleyLaboratório de Imunoparasitologia, Instituto de Ciências Médicas, Universidade Federal do Rio de Janeiro, Macaé, Brazil.ORCID 0000-0002-9707-6284

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leishmania amazonensis is one of the etiological agents of cutaneous leishmaniasis in its localised form. Moreover, this parasite can cause more severe disease conditions, such as diffuse and disseminated cutaneous leishmaniasis. The development of more severe clinical manifestations is associated with the parasite's ability to establish a chronic infection and disseminate to cutaneous tissues distal to the site of primary infection. This ability is dependent on host immune factors but is also influenced by intrinsic factors of the parasite related to pathogenicity and evasion of the immune system. This review discusses immunological and parasitological factors associated with the latency and dissemination of L. amazonensis infection and the consequent development of severe forms of cutaneous disease.

Indexed as

Immune EvasionLeishmaniaLeishmania mexicanaLeishmaniasis, CutaneousAnimalsHost-Parasite InteractionsHumansPersistent Infectiondisseminationimmune evasionlatencyLeishmania amazonensispersistencephosphatidylserine

Identifiers

PMID41500977
PMCPMC12779597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.