Evidence map›Paper›PMID 41500782›Full record

SynthesisZhongguo fei ai za zhi = Chinese journal of lung cancer2025

[Research Advances on the Autophagy and Ferroptosis 
in the Development and Treatment of Lung Cancer].

Chengqi Jiang, Xueping Cui, Li Zheng, Chengkun Deng, Ruoshan Huang, Bo Hou, Junfeng Wang

Abstract readSystematic ReviewEnglish Abstract
In one paragraph

Synthesis in Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chengqi JiangDepartment of Thoracic Surgery, Qujing Central Hospital, Qujing 655000, China.
Xueping CuiDepartment of Thoracic Surgery, Qujing Central Hospital, Qujing 655000, China.
Li ZhengDepartment of Thoracic Surgery, Qujing Central Hospital, Qujing 655000, China.
Chengkun DengDepartment of Thoracic Surgery, Qujing Central Hospital, Qujing 655000, China.
Ruoshan HuangDepartment of Thoracic Surgery, Qujing Central Hospital, Qujing 655000, China.
Bo HouDepartment of Thoracic Surgery, Qujing Central Hospital, Qujing 655000, China.
Junfeng WangDepartment of Thoracic Surgery, Qujing Central Hospital, Qujing 655000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer remains a life-threatening malignancy with complex pathogenesis. This paper provides a systematic review of autophagy and ferroptosis-related signaling pathways, key regulatory factors, and their associated mechanisms, including the nuclear receptor coactivator 4 (NCOA4)-mediated ferritin autophagy-ferroptosis axis, mitochondrial autophagy, lipid droplet autophagy, circadian autophagy, chaperone-mediated autophagy, etc.. The review elucidates the roles of the tumor microenvironment and non-coding RNAs in autophagy-ferroptosis processes in lung cancer. Furthermore, it explores the potential of modern drugs and active components from traditional Chinese medicine to improve lung cancer outcomes by targeting autophagy and ferroptosis, proposing that targeting their interactive pathways could offer novel therapeutic strategies for lung cancer.
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Indexed as

AutophagyFerroptosisLung NeoplasmsAnimalsHumansSignal TransductionTumor MicroenvironmentAutophagyFerroptosisLung neoplasmsNon-coding RNASignaling pathway

Identifiers

PMID41500782
PMCPMC12782934

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.