Evidence map›Paper›PMID 41500775›Full record

ArticleJournal for immunotherapy of cancer2026

Tumor-infiltrating microbes and therapy response: a new frontier in triple-negative breast cancer precision oncology.

Lynn M Marcho, Karthik B Chakravarthy, Sachin R Jhawar, Daniel J Spakowicz

Abstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lynn M Marcho *Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.ORCID http://orcid.org/0000-0001-6798-6458
Karthik B Chakravarthy *Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
Sachin R JhawarRadiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA Daniel.Spakowicz@osumc.edu sachin.jhawar@osumc.edu.
Daniel J SpakowiczPelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA Daniel.Spakowicz@osumc.edu sachin.jhawar@osumc.edu.ORCID http://orcid.org/0000-0003-2314-6435

Funding

Targeting immunosuppressive adenosine in patients with metastatic non-small cell lung cancerR01CA248741 · NCI · OHIO STATE UNIVERSITY · PI CARBONE, DAVID P., DIKOV, MIKHAIL M · 2021 to 2025
$3.0M
The microbiome in older adults with lung cancer: association of treatment regimens and diet with protective microbial profilesK01AG070310 · NIA · OHIO STATE UNIVERSITY · PI SPAKOWICZ, DANIEL J. · 2021 to 2025
$583k
Role of the inflammatory dietary pattern in gut and colon tissue microbiomes and impact on survival outcomes among colorectal cancer patientsR21CA294050 · NCI · OHIO STATE UNIVERSITY · PI TABUNG, FRED KINYUY · 2024 to 2024
$405k
NCI NIH HHS R01 CA248741NCI NIH HHS R21 CA294050NIA NIH HHS K01 AG070310
6 · The paper itself

Abstract

Tumor-infiltrating microbes are emerging as a novel dimension of cancer biology, with growing evidence suggesting their potential as prognostic and predictive biomarkers. In this issue, Chen

Indexed as

Precision MedicineTriple Negative Breast NeoplasmsFemaleHumansTumor MicroenvironmentBreast CancerChemotherapyImmunotherapyNeoadjuvantTumor microenvironment - TME

Identifiers

PMID41500775
PMCPMC12781984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.