ArticleBMJ case reports2026
Rosai-Dorfman disease mimicking testicular malignancy in a patient with marginal zone lymphoma of the lung.
Article in BMJ case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Primary Cutaneous Rosai-Dorfman Disease With Typical Immunophenotype But Lacking Emperipolesis: A Case Report.Clinical medicine insights. Case reports · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rosai-Dorfman-Destombes disease (RDD) is a rare, benign histiocytic disorder, most often involving lymph nodes but showing extranodal manifestations in nearly 50% of cases, particularly in the skin and upper respiratory tract. A hallmark histological feature is emperipolesis-large CD68+ and S100+ histiocytes containing intact inflammatory cells. We report a unique case of bilateral testicular RDD in a man with prior extranodal marginal zone lymphoma of the lungs. Three years after lymphoma remission, he presented with bilateral testicular enlargement. Ultrasound and positron emission tomography/CT showed diffuse hypoechoic parenchyma with metabolic activity suggestive of malignancy. Bilateral orchiectomy revealed tan-yellow, fleshy masses infiltrating the testicular parenchyma. Histology confirmed RDD with emperipolesis and S100+/CD68+/CD1a- phenotype. Testicular RDD is extremely uncommon, with only ~15 cases described to date, and its association with haematological malignancy remains poorly understood. Recognition of this entity is essential to avoid unnecessary oncological treatment.
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Registered trials
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