Evidence map›Paper›PMID 41500649›Full record

ArticleBMJ open2026

Effects of alcohol misuse on the evolution of anxiety during the COVID-19 pandemic in France: results from CONFINS cohort.

Charline Galesne, Julie Arsandaux, Mélissa Macalli, Nathalie Texier, Stéphane Schück, Christophe Tzourio, Shérazade Kinouani

Abstract read
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Charline GalesneBordeaux Population Health, University of Bordeaux College of Health Sciences, Bordeaux, France.
Julie ArsandauxLaboratoire de psychologie des Pays de la Loire, Nantes University, Nantes, France.
Mélissa MacalliBordeaux Population Health, University of Bordeaux College of Health Sciences, Bordeaux, France.
Nathalie TexierKappa Santé, Paris, France.
Stéphane SchückKappa Santé, Paris, France.
Christophe TzourioBordeaux Population Health, University of Bordeaux College of Health Sciences, Bordeaux, France.ORCID http://orcid.org/0000-0002-6517-2984
Shérazade KinouaniBordeaux Population Health, University of Bordeaux College of Health Sciences, Bordeaux, France sherazade.kinouani@u-bordeaux.fr.ORCID http://orcid.org/0000-0003-2921-008X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesto describe the evolution of anxiety during the COVID-19 pandemic in France and to assess whether it differed according to pre-existing alcohol misuse.

designA prospective longitudinal study.

settingA French online cohort: CONFINS. Data has been collected since the first lockdown in April-May 2020 until January 2022.

participants1868 participants being at least 18 years of age and who had been confined in France by government measures. PRIMARY OUTCOME MEASURE: The primary outcome was anxiety, measured through

resultsOf the 1868 included participants, 729 responded to at least one follow-up questionnaire (median follow-up time: 46 weeks). We identified 58% as having pre-existing alcohol misuse. Alcohol misuse was significantly associated with an increased GAD-7 score starting at the second lockdown in women (β=0.30; p=0.014) and in participants having a high perceived loneliness (β=0.59; p=0.011).

conclusionsPre-existing alcohol misuse appeared to be a risk factor for anxiety during the COVID-19 pandemic, particularly for women and those with high perceived loneliness. Mental health support should be proposed to these vulnerable groups in the event of a future health crisis.

Indexed as

AlcoholismAnxietyCOVID-19AdultAgedFemaleFranceGeneralized Anxiety DisorderHumansLonelinessLongitudinal StudiesMaleMiddle AgedPandemicsProspective StudiesQuarantineAnxiety disordersCOVID-19Substance misuse

Identifiers

PMID41500649
PMCPMC12778323

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.