Evidence map›Paper›PMID 41500636›Full record

ArticleBMJ open2026

Online Remote Behavioural Intervention for Tics (ORBIT-UK): protocol of a single cohort usability study.

Olivia Hastings, Beverley J Brown, Kelly-Marie Prentice, Camilla May Babbage, E Bethan Davies, Joseph Kilgariff, Tara Murphy, Glenn McGarry, Boliang Guo, Chris Greenhalgh and 2 more

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Olivia HastingsInstitute of Mental Health, Mental Health & Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0009-0009-7299-3316
Beverley J BrownInstitute of Mental Health, Mental Health & Clinical Neurosciences, University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0000-0002-1026-278X
Kelly-Marie PrenticeNIHR MindTech HealthTech Research Centre, University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0009-0000-1187-6436
Camilla May BabbageNIHR MindTech Medtech Co-operative, Institute of Mental Health, University of Nottingham Faculty of Medicine and Health Sciences, Nottingham, UK.ORCID http://orcid.org/0000-0002-6337-3352
E Bethan DaviesInstitute of Mental Health, Mental Health & Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0000-0003-3134-0879
Joseph KilgariffQueen's Medical Centre, Nottingham, Nottingham, UK.ORCID http://orcid.org/0000-0002-7195-7753
Tara MurphyUniversity College London Great Ormond Street Institute of Child Health, London, UK.
Glenn McGarrySchool of Computer Science, University of Nottingham, Nottingham, UK.
Boliang GuoPsychiatry, Institute of Mental Health, Nottingham, Nottinghamshire, UK.
Chris GreenhalghSchool of Computer Science, University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0000-0003-3483-2422
Chris HollisInstitute of Mental Health, Mental Health & Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0000-0003-1083-6744
Charlotte Lucy HallInstitute of Mental Health, Mental Health & Clinical Neurosciences, University of Nottingham, Nottingham, UK charlotte.hall@nottingham.ac.uk.ORCID http://orcid.org/0000-0002-5412-6165

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTourette syndrome is a common, disabling childhood-onset condition. Exposure and response prevention (ERP) is an effective treatment for tics, yet access remains limited due to a shortage of trained therapists and uneven geographical distribution of services. The ORBIT trial demonstrated that internet-delivered ERP is both clinically and cost-effective, but was developed on a university research platform, not suitable for widescale roll-out. To enable adoption by the National Health Service (NHS) in England, ORBIT has been redeveloped on an NHS compliant platform. This study will evaluate the usability, acceptability and preliminary outcomes of ORBIT on the new platform within an NHS tic disorder service. METHODS AND ANALYSIS: This single-cohort usability study will recruit 20 children and young people (aged 9-17) with tics and their chosen supporters (parents/carers). Participants will receive a 10-week online ERP intervention supported by trained coaches. Outcomes include uptake, adherence, system usability, satisfaction and clinical measures such as the Yale Global Tic Severity Scale, Parent Tic Questionnaire and Goal-Based Outcomes. Qualitative feedback will be collected via semi-structured exit interviews. Usability metrics and adverse events will be monitored throughout. ETHICS AND DISSEMINATION: The study has received ethical approval from North West Greater Manchester Research Ethics Committee (ref: 25/NW/0107). The findings from the study will inform future NHS adoption. The results will be submitted for publication in peer-reviewed journals. TRIAL REGISTRATION NUMBER: ISRCTN82718960. Registered 10 July 2025. https://doi.org/10.1186/ISRCTN82718960.

Indexed as

Behavior TherapyInternet-Based InterventionTicsTourette SyndromeAdolescentChildCohort StudiesEnglandFemaleHumansInternetMaleResearch DesignState MedicineTelemedicineUnited KingdomChild & adolescent psychiatryClinical ProtocolsDevelopmental neurology & neurodisabilityDigital TechnologyMENTAL HEALTHPaediatric neurology

Identifiers

PMID41500636
PMCPMC12781982

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.